Reactome | Synthesis of UDP-N-acetyl-glucosamine

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Synthesis of UDP-N-acetyl-glucosamine Show undefined attributes

created	[InstanceEdit:10203599] Wright, Adam, 2024-03-07
dbId	10312552
displayName	Synthesis of UDP-N-acetyl-glucosamine
eventOf	[Pathway:R-BTA-446219] Synthesis of substrates in N-glycan biosythesis - Bos taurus
evidenceType	[EvidenceType:9864366] inferred by electronic annotation
goBiologicalProcess	[GO_BiologicalProcess:14887] UDP-N-acetylglucosamine biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-BTA-6803761] RENBP isomerises ManNAc, ManNGc to GlcNAc, GlcNGc - Bos taurus [Reaction:R-BTA-6803771] NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P - Bos taurus [Reaction:R-BTA-6803789] AMDHD2 hydrolyses GlcNGc-6-P to GlcN6P and CCA - Bos taurus [Reaction:R-BTA-449715] GFPT1,2 transfer an amino group from L-Gln to F6P to form GlcN6P - Bos taurus [Reaction:R-BTA-449734] Acetylation of glucosamine 6-phosphate to GlcNAc6P - Bos taurus [Reaction:R-BTA-446185] Isomerization of GlcNAc6P to GlcNAc1P - Bos taurus [Reaction:R-BTA-446204] GlcNAc1P is dephosphorylated to UDP-N-acetyl-glucosamine - Bos taurus
inferredFrom	[Pathway:R-HSA-446210] Synthesis of UDP-N-acetyl-glucosamine - Homo sapiens
isInDisease	false
isInferred	true
name	Synthesis of UDP-N-acetyl-glucosamine
releaseDate	2024-03-27
schemaClass	Pathway
species	[Species:48898] Bos taurus
stId	R-BTA-446210
summation	[Summation:9864365] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-BTA-446219] Synthesis of substrates in N-glycan biosythesis
(inferredTo)	[Pathway:R-HSA-446210] Synthesis of UDP-N-acetyl-glucosamine

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