Search results for (p42 127)

Showing 30 results out of 75

×

Species

Types

Compartments

Reaction types

Search properties

Species

Types

Compartments

Reaction types

Search properties

Results (30 results from a total of 75)

Identifier: R-HSA-381455
Species: Homo sapiens
Compartment: extracellular region
Primary external reference: UniProt: IGFBP3: P17936
Identifier: R-HSA-381699
Species: Homo sapiens
Compartment: extracellular region
Primary external reference: UniProt: GCG: P01275
The amide group at the C-terminus is not necessary for biological activity.
Identifier: R-HSA-421419
Species: Homo sapiens
Compartment: secretory granule lumen
Primary external reference: UniProt: GCG: P01275
Identifier: R-HSA-400534
Species: Homo sapiens
Compartment: extracellular region
Primary external reference: UniProt: GCG: P01275
Identifier: Q496Y0
Species: Homo sapiens
Primary external reference: UniProt: Q496Y0
Identifier: Q00532
Species: Homo sapiens
Primary external reference: UniProt: Q00532
Identifier: Q8IZL9
Species: Homo sapiens
Primary external reference: UniProt: Q8IZL9
Identifier: P46672
Species: Saccharomyces cerevisiae
Primary external reference: UniProt: P46672
Identifier: Q13064
Species: Homo sapiens
Primary external reference: UniProt: Q13064
Identifier: Q9NQZ6
Species: Homo sapiens
Primary external reference: UniProt: Q9NQZ6
Identifier: EBI-9939807
Species: Drosophila melanogaster
Primary external reference: IntAct: EBI-9939807
Identifier: R-HSA-9727908
Species: Homo sapiens
Compartment: cytosol
SARS-CoV-1 nucleocapsid protein interacts with proteasome subunit p42 (PSMC6). Proteasomes play a central role in the degradation of short-lived and regulatory host proteins. They are also capable of degrading exogenous proteins like viral peptides (Wang et al, 2010).
Identifier: R-HSA-1471317
Species: Homo sapiens
Compartment: extracellular region
Primary external reference: UniProt: DEFB127: Q9H1M4
Identifier: R-HSA-975809
Species: Homo sapiens
Compartment: Golgi lumen
Primary external reference: UniProt: DEFB127: Q9H1M4
Identifier: R-RNO-381455
Species: Rattus norvegicus
Compartment: extracellular region
Primary external reference: UniProt: P15473
Identifier: R-DRE-381455
Species: Danio rerio
Compartment: extracellular region
Primary external reference: UniProt: Q66I28
Identifier: R-HSA-1470031
Species: Homo sapiens
Compartment: Golgi lumen
Primary external reference: UniProt: DEFB127: Q9H1M4
Identifier: R-MMU-9676907
Species: Mus musculus
Compartment: cytosol, nucleoplasm
Homodimers of phosphorylated Stat1, Stat3, and Stat5 and heterodimers of phosphorylated Stat1 and Stat3 translocate from the cytosol to the nucleus (Nicholson et al. 1995, de Koning et al. 1996, Ward et al. 1999, Gits et al. 2006).
Identifier: R-HSA-9759811
Species: Homo sapiens
Several microRNAs are implicated in posttranscriptional regulation of CDH11 gene expression. The diagram only shows microRNAs reported to downregulate CDH11 mRNA and/or protein levels by at least 2 studies, with at least one study providing human evidence, and at least one study providing mechanistic evidence in the form of luciferase reporter assay and/or formation of the microRNA-mRNA complex. For a more detailed description of criteria for microRNA annotation please refer to Huntely et al. 2016.

The following CDH11-targeting microRNAs are strongly supported by experimental evidence and directly shown in the diagram:
miR-200c-3p (Luo et al. 2013; Van der Goten et al. 2014)
miR-451a (Yamada et al. 2018; Wang et al. 2020; Wang et al. 2021)

The following microRNAs probably target CDH11, but additional evidence is needed to directly represent them in the diagram:
miR-103-2-5p (Gao et al. 2020)
miR-127-3p (Dong et al. 2021)
miR-148-5p (Kawagoe et al. 2020)
Identifier: R-MMU-9674931
Species: Mus musculus
Compartment: plasma membrane
After phosphorylation while bound to phospho-Csf3r at the plasma membrane, p-Stat1,3,5 dissociates from Csf3r prior to dimerizing and transiting to the nucleus (Nicholson et al. 1995, de Koning et al. 1996, Nicholson et al. 1996, Gits et al. 2006).
Identifier: R-HSA-68783
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: PSMC6: P62333
Identifier: R-HSA-174319
Species: Homo sapiens
Compartment: nucleoplasm
Primary external reference: UniProt: PSMC6: P62333
Identifier: R-HSA-5674387
Species: Homo sapiens
Compartment: nucleoplasm
After phosphorylation by MAP2Ks, a proportion of activated MAPK translocates into the nucleus where it activates nuclear targets (reviewed in Roskoski, 2012b). MAPKs, which lack a nuclear localization signal (NLS), may 'piggyback' into the nucleus in complex with other nuclear-targeted proteins or may translocate by virtue of interaction with components of the nuclear pore complex (Brunet et al, 1999; Adachi et al, 1999; Matsubayashi et al, 2001; Whitehurst et al, 2002; Khokhlatchev et al, 1998; reviewed in Roskoski, 2012b). Although dimerization of MAPKs was thought to be critical for nuclear translocation, a number of studies have now challenged the physiological relevance of MAPK dimerization and this remains an area of uncertainty (Lenormand et al, 1993; Chen et al, 1992; Casar et al, 2008; Lidke et al, 2010; Burack and Shaw, 2005; reviewed in Casar et al, 2009; Roskoski, 2012b)
Identifier: R-MMU-9676072
Species: Mus musculus
Compartment: plasma membrane
The kinases Jak2 (Nicholson et al. 1995, Avalos et al. 1997), Tyk2 (Novak et al. 1996, Avalos et al. 1997), Hck (Ward et al. 1998, Santini et al. 2003), and Syk (Corey et al. 1994, Santini et al. 2003) bind phosphorylated tyrosine residues of the cytosolic domain of Csf3r and are activated by phosphorylation.
Identifier: R-HSA-59282
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: MAPK1: P28482
Identifier: R-HSA-199960
Species: Homo sapiens
Compartment: nucleoplasm
Primary external reference: UniProt: MAPK1: P28482
Identifier: R-HSA-6800964
Species: Homo sapiens
Compartment: ficolin-1-rich granule lumen
Primary external reference: UniProt: MAPK1: P28482
Identifier: R-HSA-6806250
Species: Homo sapiens
Compartment: extracellular region
Primary external reference: UniProt: MAPK1: P28482
Identifier: R-HSA-6799225
Species: Homo sapiens
Compartment: azurophil granule lumen
Primary external reference: UniProt: MAPK1: P28482
Identifier: R-HSA-9636293
Species: Homo sapiens
Compartment: endoplasmic reticulum lumen
Primary external reference: UniProt: MAPK1: P28482
Cite Us!