Guanine + H2O => Xanthine + NH4+

Stable Identifier
R-HSA-74255
Type
Reaction
Species
Homo sapiens
Compartment
Locations in the PathwayBrowser
Summation

Cytosolic guanine deaminase (GDA) catalyzes the reaction of guanine and water to form xanthine and ammonia (Yuan et al. 1999). The active enzyme is a homodimer (Murphy et al. 2009).

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
guanine deaminase activity of GDA dimer [cytosol]
Physical Entity
Activity
Orthologous Events
Cross References
Rhea