Reactome | nr3c1 [nucleoplasm]

nr3c1 [nucleoplasm]

Stable Identifier

R-XTR-4341106

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

nucleoplasm

Synonyms

SUMO1-K277,K293-NR3C1, Q28E31

Locations in the PathwayBrowser

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Metabolism of proteins (Xenopus tropicalis)

- Post-translational protein modification (Xenopus tropicalis)
  - SUMOylation (Xenopus tropicalis)
    - SUMO E3 ligases SUMOylate target proteins (Xenopus tropicalis)
      - SUMOylation of intracellular receptors (Xenopus tropicalis)
        
        SUMOylation of NR3C1 (GR) with SUMO1 (Xenopus tropicalis)
        
        2SUMO1:NR3C1:Glucocorticoid ligand dimer [nucleoplasm] (Xenopus tropicalis)
        
        2SUMO1:NR3C1:Glucocorticoid ligand [nucleoplasm] (Xenopus tropicalis)
        
        nr3c1 [nucleoplasm] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:Q28E31

Gene Names

nr3c1

Reference Genes

BioGPS Gene:549721 nr3c1

ENSEMBL:ENSXETG00000042129

KEGG Gene (Xenopus tropicalis):549721 nr3c1

Monarch:549721 nr3c1

NCBI Gene:549721 nr3c1

Reference Transcript

RefSeq:NM_001016967.2 nr3c1

Other Identifiers

549721

GO:0003677

GO:0003700

GO:0004883

GO:0005496

GO:0005634

GO:0005737

GO:0005739

GO:0005813

GO:0005815

GO:0005819

GO:0005856

GO:0006325

GO:0006351

GO:0006355

GO:0008270

GO:0008289

GO:0023052

GO:0042921

GO:0043226

GO:0043402

GO:0043565

GO:0046872

GO:0060089

GO:0140110

Participates

as a component of

2SUMO1:NR3C1:Glucocorticoid ligand [nucleoplasm] (Xenopus tropicalis)

Other forms of this molecule

nr3c1 [cytosol]

nr3c1 [nucleoplasm]

Inferred From

SUMO1-K277,K293-NR3C1 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 277 (in Homo sapiens)

Coordinate

277

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Name

sumoylated lysine (monoSUMO1 [nucleoplasm]) at 293 (in Homo sapiens)

Coordinate

293

Modification

monoSUMO1 [nucleoplasm]

PsiMod Name

sumoylated lysine

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a sumo (Small Ubiquitin-related MOdifier) protein.

Cross References

RefSeq

NP_001016967.1

Xenbase

XB-GENE-484757

Ensembl

ENSXETG00000042129, ENSXETT00000106174, ENSXETP00000117231

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