Reactome | wasf1 [cytosol]

wasf1 [cytosol]

Stable Identifier

R-XTR-200965

Type

Protein [EntityWithAccessionedSequence]

Species

Xenopus tropicalis

Compartment

cytosol

Synonyms

WASF1, F6W481

Locations in the PathwayBrowser

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Immune System (Xenopus tropicalis)

- Innate Immune System (Xenopus tropicalis)
  - Fcgamma receptor (FCGR) dependent phagocytosis (Xenopus tropicalis)
    - Regulation of actin dynamics for phagocytic cup formation (Xenopus tropicalis)
      - ABL phosphorylates WAVEs (Xenopus tropicalis)
        
        WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        WAVEs [cytosol] (Xenopus tropicalis)
        
        wasf1 [cytosol] (Xenopus tropicalis)

Signal Transduction (Xenopus tropicalis)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
  - Signaling by Rho GTPases (Xenopus tropicalis)
    - RHO GTPase Effectors (Xenopus tropicalis)
      - RHO GTPases Activate WASPs and WAVEs (Xenopus tropicalis)
        
        ABL phosphorylates WAVEs (Xenopus tropicalis)
        
        WRC:IRSp53/58:RAC1:GTP:PIP3 [plasma membrane] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        WAVEs [cytosol] (Xenopus tropicalis)
        
        wasf1 [cytosol] (Xenopus tropicalis)
    - RHO GTPase cycle (Xenopus tropicalis)
      - RAC1 GTPase cycle (Xenopus tropicalis)
        
        RAC1 binds effectors at the plasma membrane (Xenopus tropicalis)
        
        RAC1 effectors [cytosol] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        WAVEs [cytosol] (Xenopus tropicalis)
        
        wasf1 [cytosol] (Xenopus tropicalis)
        
        RAC1:GTP:RAC1 effectors [plasma membrane] (Xenopus tropicalis)
        
        RAC1 effectors [cytosol] (Xenopus tropicalis)
        
        WAVE Regulatory Complex [cytosol] (Xenopus tropicalis)
        
        WAVEs [cytosol] (Xenopus tropicalis)
        
        wasf1 [cytosol] (Xenopus tropicalis)

External Reference Information

External Reference

UniProt:F6W481

Gene Names

wasf1

Reference Genes

BioGPS Gene:100124768 wasf1

ENSEMBL:ENSXETG00000021311

KEGG Gene (Xenopus tropicalis):100124768 wasf1

Monarch:100124768 wasf1

NCBI Gene:100124768 wasf1

Reference Transcript

Other Identifiers

100124768

GO:0003779

GO:0005737

GO:0005856

GO:0007010

GO:0008092

GO:0030036

GO:0043226

Participates

as a candidate of

WAVEs [cytosol] (Xenopus tropicalis)

Other forms of this molecule

phospho-wasf1 [cytosol]

Inferred From

WASF1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001096217.1, XP_012818068.1

Xenbase

XB-GENE-978145

Ensembl

ENSXETT00000046096, ENSXETP00000046096, ENSXETG00000021311

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