Reactome | CDK4 [cytosol]

CDK4 [cytosol]

Stable Identifier

R-SSC-68330

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

P79432

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by Non-Receptor Tyrosine Kinases (Sus scrofa)
  - Signaling by PTK6 (Sus scrofa)
    - PTK6 Regulates Cell Cycle (Sus scrofa)
      - Activated PTK6 binds CDKN1B (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        CDK4:CCND1 [cytosol] (Sus scrofa)
        
        CDK4 [cytosol] (Sus scrofa)
        
        p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        CDK4:CCND1 [cytosol] (Sus scrofa)
        
        CDK4 [cytosol] (Sus scrofa)
      - PTK6 phosphorylates CDKN1B (Sus scrofa)
        
        p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        CDK4:CCND1 [cytosol] (Sus scrofa)
        
        CDK4 [cytosol] (Sus scrofa)
        
        p-Y88-CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        CDK4:CCND1 [cytosol] (Sus scrofa)
        
        CDK4 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:P79432

Reference Genes

BioGPS Gene:100144492

ENSEMBL:ENSSSCG00000025092.4

ENSEMBL:ENSSSCG00005038121.1

ENSEMBL:ENSSSCG00015021039.1

ENSEMBL:ENSSSCG00025022032.1

ENSEMBL:ENSSSCG00030064224.1

ENSEMBL:ENSSSCG00035007972.1

ENSEMBL:ENSSSCG00040055398.1

ENSEMBL:ENSSSCG00045011047.1

ENSEMBL:ENSSSCG00050000908.1

ENSEMBL:ENSSSCG00055018402.1

ENSEMBL:ENSSSCG00060005787.1

ENSEMBL:ENSSSCG00065004166.1

ENSEMBL:ENSSSCG00070028938.1

KEGG Gene (Sus scrofa):100144492

Monarch:100144492

NCBI Gene:100144492

Reference Transcript

RefSeq:NM_001123097.1

Other Identifiers

100144492

GO:0000082

GO:0000278

GO:0000307

GO:0000785

GO:0003824

GO:0004672

GO:0004693

GO:0005524

GO:0005634

GO:0005635

GO:0005654

GO:0005667

GO:0005694

GO:0005730

GO:0005829

GO:0005923

GO:0006468

GO:0007165

GO:0008284

GO:0009410

GO:0010468

GO:0010971

GO:0016301

GO:0016740

GO:0023052

GO:0030332

GO:0031965

GO:0036211

GO:0043226

GO:0048146

GO:0051726

GO:0061469

GO:0071222

GO:0071353

GO:0097128

GO:0097129

GO:0097130

GO:0140096

GO:1904628

GO:1904637

Ssc.11051.1.S1_at

Participates

as a component of

as a member of

CDK4,CDK6 [cytosol] (Sus scrofa)

Other forms of this molecule

CDK4 [nucleoplasm]

phospho-p-T172-CDK4 [nucleoplasm]

Inferred From

CDK4 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_001116569.1

Ensembl

ENSSSCG00000025092, ENSSSCP00000022407, ENSSSCT00000028348

VGNC

86504

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