Reactome | ELL2 [nucleoplasm]

ELL2 [nucleoplasm]

Stable Identifier

R-SSC-6807506

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

nucleoplasm

Synonyms

ELL2, A0A480JTG5

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Sus scrofa)

- RNA Polymerase II Transcription (Sus scrofa)
  - RNA polymerase II transcribes snRNA genes (Sus scrofa)
    - CBCAP complex binds 7-methylguanosine cap of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Sus scrofa)
        
        ELL2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Sus scrofa)
        
        ELL2 [nucleoplasm] (Sus scrofa)
    - Integrator complex processes the 3' end of snRNA (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Sus scrofa)
        
        ELL2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Sus scrofa)
        
        ELL2 [nucleoplasm] (Sus scrofa)
    - Pre-snRNA is elongated and capped with 7-methylguanosine (Sus scrofa)
      - RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser2,7 CTD):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Sus scrofa)
        
        ELL2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Sus scrofa)
        
        ELL2 [nucleoplasm] (Sus scrofa)
    - Pre-snRNA transcript initiation, Integrator binding, LEC binding (Sus scrofa)
      - LEC [nucleoplasm] (Sus scrofa)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Sus scrofa)
        
        ELL2 [nucleoplasm] (Sus scrofa)
      - RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
        
        RNA polymerase II (phospho-Ser5,7 CTD):RDRP1A,B:RDRP2:RPAP2:Integrator:LEC [nucleoplasm] (Sus scrofa)
        
        LEC [nucleoplasm] (Sus scrofa)
        
        ELL,ELL2,ELL3 [nucleoplasm] (Sus scrofa)
        
        ELL2 [nucleoplasm] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A480JTG5

Gene Names

ELL2

Reference Genes

BioGPS Gene:100523777 ELL2

ENSEMBL:ENSSSCG00000014168.5

KEGG Gene (Sus scrofa):100523777 ELL2

Monarch:100523777 ELL2

NCBI Gene:100523777 ELL2

Reference Transcript

RefSeq:XM_003123796.4 ELL2

Other Identifiers

100523777

GO:0003746

GO:0005634

GO:0005654

GO:0006351

GO:0006366

GO:0006368

GO:0006414

GO:0008023

GO:0016073

GO:0042795

GO:0043226

GO:0045182

Participates

as a member of

ELL,ELL2,ELL3 [nucleoplasm] (Sus scrofa)

Inferred From

ELL2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

XP_003123844.2

OpenTargets

ENSG00000118985

Ensembl

ENSSSCG00000014168, ENSSSCT00000102858, ENSSSCP00000080686