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MAPK1 [cytosol]
Stable Identifier
R-SSC-59282
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
A0A5G2RG05
Locations in the PathwayBrowser
Expand all
Developmental Biology (Sus scrofa)
Nervous system development (Sus scrofa)
Axon guidance (Sus scrofa)
L1CAM interactions (Sus scrofa)
Signal transduction by L1 (Sus scrofa)
MAP2K2 phosphorylates MAPK1 (Sus scrofa)
p-S,T-MAP2K2:MAPK1 [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
Hemostasis (Sus scrofa)
Platelet activation, signaling and aggregation (Sus scrofa)
Thrombin signalling through proteinase activated receptors (PARs) (Sus scrofa)
Activated SRC-1 activates MAPKs (in F2R:ARRB1:MAPKs:active SRC-1) (Sus scrofa)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
F2R:ARRB1 binds MAPKs, SRC-1 (Sus scrofa)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
F2R:ARRB2 binds MAPKs, SRC-1 (Sus scrofa)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
SRC-1 bound to ARRB2 is not activated (Sus scrofa)
F2R:ARRB2:MAPKs:SRC-1 [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
SRC-1 is activated (in F2R:ARRB1:MAPKs:SRC-1) (Sus scrofa)
F2R:ARRB1:MAPKs:SRC-1 [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Growth hormone receptor signaling (Sus scrofa)
Lyn activates ERK (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
Interferon Signaling (Sus scrofa)
Interferon gamma signaling (Sus scrofa)
IFNG signaling activates MAPKs (Sus scrofa)
JAK1-activated RAF1 phosphorylates MAPKs (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF-independent MAPK1/3 activation (Sus scrofa)
Cytosolic DUSPs dephosphorylate MAPKs (Sus scrofa)
MAPK monomers and dimers [cytosol] (Sus scrofa)
MAPK1 dimer [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAPK1 (ERK2) activation (Sus scrofa)
MAP2K2 binds MAPK1 (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
p-S,T-MAP2K2:MAPK1 [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAP2K2 phosphorylates MAPK1 (Sus scrofa)
p-S,T-MAP2K2:MAPK1 [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
MAP2K and MAPK activation (Sus scrofa)
Dual mechanism MAP2K inhibitors bind MAP2Ks (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
Dual mechanism MAPK inhibitors bind MAPKs (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
IL17RD binds p-2S MAP2Ks and MAPKs (Sus scrofa)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Sus scrofa)
WDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAP2Ks and MAPKs bind to the activated RAF complex (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Sus scrofa)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPKs (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
RAF phosphorylates MAP2K dimer (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex:dual mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
WDR83:LAMTOR2:LAMTOR3 binds MAPK components (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
WDR83:LAMTOR2:LAMTOR3:activated RAF:MAP2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
Negative regulation of MAPK pathway (Sus scrofa)
Cytosolic DUSPs dephosphorylate MAPKs (Sus scrofa)
MAPK monomers and dimers [cytosol] (Sus scrofa)
MAPK1 dimer [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by Insulin receptor (Sus scrofa)
Insulin receptor signalling cascade (Sus scrofa)
Signal attenuation (Sus scrofa)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Sus scrofa)
MAPK3,(MAPK1) [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Sus scrofa)
MAPK3,(MAPK1) [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
Signaling by NTRKs (Sus scrofa)
Signaling by NTRK1 (TRKA) (Sus scrofa)
Signalling to ERKs (Sus scrofa)
Prolonged ERK activation events (Sus scrofa)
Frs2-mediated activation (Sus scrofa)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Sus scrofa)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
Activated BRAF recruits MAP2Ks and MAPKs to the endosome (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
RAP1:GTP:activated BRAF dimer:MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
MAPKs [cytosol] (Sus scrofa)
MAPK1 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A5G2RG05
Reference Genes
ENSEMBL:ENSSSCG00000010081.6
Other Identifiers
100153927
GO:0000165
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0005524
GO:0005634
GO:0005737
GO:0005768
GO:0005769
GO:0005770
GO:0005794
GO:0005856
GO:0005886
GO:0005901
GO:0005925
GO:0006468
GO:0007010
GO:0007166
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0031410
GO:0032872
GO:0035556
GO:0036211
GO:0043226
GO:0051493
GO:0072584
GO:0090170
GO:0106310
GO:0140096
GO:2000641
Ssc.4068.1.S1_at
Ssc.5106.1.S1_at
Participates
as a candidate of
MAPK3,(MAPK1) [cytosol] (Sus scrofa)
as a component of
MAPK1 dimer [cytosol] (Sus scrofa)
p-S,T-MAP2K2:MAPK1 [cytosol] (Sus scrofa)
as an input of
MAP2K2 binds MAPK1 (Sus scrofa)
as a member of
MAPKs [cytosol] (Sus scrofa)
Other forms of this molecule
MAPK1 [azurophil granule lumen]
MAPK1 [extracellular region]
MAPK1 [ficolin-1-rich granule lumen]
MAPK1 [nucleoplasm]
phospho-p-T185,Y187-MAPK1 [cytosol]
phospho-p-T185,Y187-MAPK1 [nucleoplasm]
Inferred From
MAPK1 [cytosol]
(Homo sapiens)
Cross References
Ensembl
ENSSSCP00000073842
,
ENSSSCT00000066579
,
ENSSSCG00000010081
VGNC
89996
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