Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
p-S222,S226 MAP2K2 dimer [cytosol]
Stable Identifier
R-SSC-5672701
Type
Complex
Species
Sus scrofa
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
MAP2K and MAPK activation (Sus scrofa)
Dissociation of RAS:RAF complex (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
Dual mechanism MAPK inhibitors bind MAPKs (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
IL17RD binds p-2S MAP2Ks and MAPKs (Sus scrofa)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Sus scrofa)
WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex [endosome membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Sus scrofa)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
IL17RD:p-2S MAP2Ks:p-T,Y MAPKs [Golgi membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPKs (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
RAF phosphorylates MAP2K dimer (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
RAF activation (Sus scrofa)
Phosphorylation of RAF (Sus scrofa)
RAF activating kinases [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by NTRKs (Sus scrofa)
Signaling by NTRK1 (TRKA) (Sus scrofa)
Signalling to ERKs (Sus scrofa)
Prolonged ERK activation events (Sus scrofa)
Frs2-mediated activation (Sus scrofa)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
Dissociation of phosphorylated MAP2Ks and MAPKs (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
phospho-p-S222,S226-MAP2K2 [cytosol]
(Sus scrofa)
Participates
as a component of
IL17RD:p-2S MAP2Ks:p-T,Y MAPKs [Golgi membrane] (Sus scrofa)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Sus scrofa)
WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex [endosome membrane] (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
as an input of
IL17RD binds p-2S MAP2Ks and MAPKs (Sus scrofa)
as an output of
Dissociation of phosphorylated MAP2Ks and MAPKs (Sus scrofa)
Dissociation of RAS:RAF complex (Sus scrofa)
as a candidate of
RAF activating kinases [plasma membrane] (Sus scrofa)
Inferred From
p-2S MAP2K homo/heterodimers [cytosol]
(Homo sapiens)
p-S222,S226 MAP2K2 dimer [cytosol]
(Homo sapiens)
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text