Reactome | SGO1 [cytosol]

SGO1 [cytosol]

Stable Identifier

R-SSC-376227

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

SGOL1, F1RS59

Locations in the PathwayBrowser

Expand all

Cell Cycle (Sus scrofa)

- Cell Cycle Checkpoints (Sus scrofa)
  - Mitotic Spindle Checkpoint (Sus scrofa)
    - Amplification of signal from the kinetochores (Sus scrofa)
      - Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal (Sus scrofa)
        
        MAD2 associates with the Mad1 kinetochore complex (Sus scrofa)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Sus scrofa)
        
        Mad1:kinetochore complex [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Mad1:kinetochore complex [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        MAD2 converted to an inhibitory state via interaction with Mad1 (Sus scrofa)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Sus scrofa)
        
        Mad1:kinetochore complex [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Mad1 binds kinetochore (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Mad1:kinetochore complex [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Release of activated MAD2 from kinetochores (Sus scrofa)
        
        Kinetochore:Mad1:MAD2 Complex [cytosol] (Sus scrofa)
        
        Mad1:kinetochore complex [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Mad1:kinetochore complex [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
- Cell Cycle, Mitotic (Sus scrofa)
  - M Phase (Sus scrofa)
    - Mitotic Metaphase and Anaphase (Sus scrofa)
      - Mitotic Anaphase (Sus scrofa)
        
        Separation of Sister Chromatids (Sus scrofa)
        
        ESPL1 (Separase) cleaves centromeric cohesin (Sus scrofa)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Microtubule-bound kinetochore [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Separation of sister chromatids (Sus scrofa)
        
        Cleaved Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Sister Centromere:Kinetochore:Microtubules [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
    - Mitotic Prometaphase (Sus scrofa)
      - EML4 and NUDC in mitotic spindle formation (Sus scrofa)
        
        EML4 recruits NUDC to mitotic spindle (Sus scrofa)
        
        Microtubule-bound kinetochore [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        p-S274,S326-NUDC:EML4 homotrimer:Microtubule-bound kinetochore [spindle] (Sus scrofa)
        
        Microtubule-bound kinetochore [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
      - Kinetochore capture of astral microtubules (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Microtubule-bound kinetochore [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
      - Resolution of Sister Chromatid Cohesion (Sus scrofa)
        
        CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Sus scrofa)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Microtubule-bound kinetochore [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Kinetochore assembly (Sus scrofa)
        
        Ac-Cohesin:PDS5:CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Ac-Cohesin:PDS5:WAPAL:Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Sister Centromere:Kinetochore [chromosome, centromeric region] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Microtubule-bound kinetochore [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        PP2A-B56 dephosphorylates centromeric cohesin (Sus scrofa)
        
        p-RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Microtubule-bound kinetochore [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Microtubule-bound kinetochore [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        Phosphorylation of cohesin by PLK1 at centromeres (Sus scrofa)
        
        Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Microtubule-bound kinetochore [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)
        
        p-STAG2,RAD21-Ac-Cohesin:PDS5:p-CDCA5:WAPAL:Sister Centromeres:Kinetochores:Microtubules [chromosome, centromeric region] (Sus scrofa)
        
        Microtubule-bound kinetochore [cytosol] (Sus scrofa)
        
        Kinetochore [cytosol] (Sus scrofa)
        
        SGO1 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RS59

Gene Names

SGO1

Reference Genes

BioGPS Gene:100520101 SGO1

ENSEMBL:ENSSSCG00000011207.4

KEGG Gene (Sus scrofa):100520101 SGO1

Monarch:100520101 SGO1

NCBI Gene:100520101 SGO1

Reference Transcript

RefSeq:XM_003132070.3 SGO1

Other Identifiers

100520101

GO:0000278

GO:0000775

GO:0000776

GO:0000779

GO:0000922

GO:0005634

GO:0005654

GO:0005694

GO:0005813

GO:0005815

GO:0005829

GO:0005856

GO:0007010

GO:0007049

GO:0007059

GO:0008608

GO:0010457

GO:0016043

GO:0019900

GO:0022414

GO:0043226

GO:0045132

GO:0051301

GO:0071962

GO:0140013

GO:0140014

Participates

as a component of

Kinetochore [cytosol] (Sus scrofa)

Inferred From

SGOL1 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_003132118.1

OpenTargets

ENSG00000129810

Ensembl

ENSSSCP00000011956, ENSSSCT00000012273, ENSSSCG00000011207

VGNC

92796

Cite Us!