Reactome | ITGB5 [plasma membrane]

ITGB5 [plasma membrane]

Stable Identifier

R-SSC-215948

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

ITGB5, A0A287AZ66

Locations in the PathwayBrowser

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Immune System (Sus scrofa)

- Adaptive Immune System (Sus scrofa)
  - Class I MHC mediated antigen processing & presentation (Sus scrofa)
    - Antigen processing-Cross presentation (Sus scrofa)
      - Cross-presentation of particulate exogenous antigens (phagosomes) (Sus scrofa)
        
        Engulfment of particulate antigen into phagocytic vesicle (Sus scrofa)
        
        Particulate Ag:DC receptors [plasma membrane] (Sus scrofa)
        
        DC receptors recognizing apoptotic cells [plasma membrane] (Sus scrofa)
        
        Integrin alphaVbeta5 [plasma membrane] (Sus scrofa)
        
        ITGB5 [plasma membrane] (Sus scrofa)
        
        Interaction of particulate antigens with dendritic cell receptors (Sus scrofa)
        
        DC receptors recognizing apoptotic cells [plasma membrane] (Sus scrofa)
        
        Integrin alphaVbeta5 [plasma membrane] (Sus scrofa)
        
        ITGB5 [plasma membrane] (Sus scrofa)
        
        Particulate Ag:DC receptors [plasma membrane] (Sus scrofa)
        
        DC receptors recognizing apoptotic cells [plasma membrane] (Sus scrofa)
        
        Integrin alphaVbeta5 [plasma membrane] (Sus scrofa)
        
        ITGB5 [plasma membrane] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by TGFB family members (Sus scrofa)
  - Signaling by TGF-beta Receptor Complex (Sus scrofa)
    - TGF-beta receptor signaling activates SMADs (Sus scrofa)
      - Latent TGF-beta-1 binds integrins (Sus scrofa)
        
        LAP1 binding-integrins [plasma membrane] (Sus scrofa)
        
        Integrin alphaVbeta5 [plasma membrane] (Sus scrofa)
        
        ITGB5 [plasma membrane] (Sus scrofa)
        
        LTBP1:TGFB1:LAP1:LAP1-binding integrins [plasma membrane] (Sus scrofa)
        
        LAP1 binding-integrins [plasma membrane] (Sus scrofa)
        
        Integrin alphaVbeta5 [plasma membrane] (Sus scrofa)
        
        ITGB5 [plasma membrane] (Sus scrofa)
      - Latent TGF-beta-3 binds integrins (Sus scrofa)
        
        LAP3-binding integrins [plasma membrane] (Sus scrofa)
        
        Integrin alphaVbeta5 [plasma membrane] (Sus scrofa)
        
        ITGB5 [plasma membrane] (Sus scrofa)
        
        TGF-beta-3:LAP3:LAP3-binding integrins [plasma membrane] (Sus scrofa)
        
        LAP3-binding integrins [plasma membrane] (Sus scrofa)
        
        Integrin alphaVbeta5 [plasma membrane] (Sus scrofa)
        
        ITGB5 [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287AZ66

Gene Names

ITGB5

Reference Genes

ENSEMBL:ENSSSCG00000037905.3

Other Identifiers

100134977

GO:0005178

GO:0005886

GO:0005925

GO:0007010

GO:0007155

GO:0007160

GO:0007179

GO:0007229

GO:0008305

GO:0009986

GO:0016020

GO:0016477

GO:0023052

GO:0030154

GO:0034684

GO:0035987

GO:0043149

GO:0043235

GO:0048856

GO:0048870

GO:0090136

Ssc.26290.1.S1_at

Participates

as a component of

Other forms of this molecule

ITGB5 [phagocytic vesicle]

Inferred From

ITGB5 [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000082781

Ensembl

ENSSSCT00000052970, ENSSSCP00000049436, ENSSSCG00000037905

VGNC

89244

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