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phospho-p-S222,S226-MAP2K2 [cytosol]
Stable Identifier
R-SSC-169292
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
K7GPS0
Locations in the PathwayBrowser
Expand all
Signal Transduction (Sus scrofa)
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF/MAP kinase cascade (Sus scrofa)
MAP2K and MAPK activation (Sus scrofa)
Dissociation of RAS:RAF complex (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
Dual mechanism MAPK inhibitors bind MAPKs (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
IL17RD binds p-2S MAP2Ks and MAPKs (Sus scrofa)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Sus scrofa)
WDR83:LAMTOR2:LAMTOR3:activated RAF:p-2S MAP2K:p-T,Y MAPK complex [endosome membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Sus scrofa)
IL17RD:p-2S MAP2Ks:MAPKs [Golgi membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
IL17RD:p-2S MAP2Ks:p-T,Y MAPKs [Golgi membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPKs (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:dual mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
RAF phosphorylates MAP2K dimer (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
Single mechanism MAP2K inhibitors bind phosphorylated MAP2Ks (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK:single mechanism MAP2K inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
Single mechanism MAPK inhibitors bind phosphorylated MAPK (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK:single mechanism MAPK inhibitors [plasma membrane] (Sus scrofa)
activated RAF:scaffold:p-2S MAP2K:p-2T MAPK complex [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
RAF activation (Sus scrofa)
Phosphorylation of RAF (Sus scrofa)
RAF activating kinases [plasma membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by NTRKs (Sus scrofa)
Signaling by NTRK1 (TRKA) (Sus scrofa)
Signalling to ERKs (Sus scrofa)
Prolonged ERK activation events (Sus scrofa)
Frs2-mediated activation (Sus scrofa)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
Dissociation of phosphorylated MAP2Ks and MAPKs (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:MAPK complex [endosome membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
RAP1:GTP:activated BRAF dimer:p-2S MAPK2K:p-T,Y MAPK complex [endosome membrane] (Sus scrofa)
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
phospho-p-S222,S226-MAP2K2 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:K7GPS0
Reference Genes
BioGPS Gene:100525505
ENSEMBL:ENSSSCG00000027127.5
KEGG Gene (Sus scrofa):100525505
Monarch:100525505
NCBI Gene:100525505
Reference Transcript
RefSeq:NM_001244550.1
Other Identifiers
100525505
GO:0000165
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004708
GO:0005078
GO:0005524
GO:0005783
GO:0005794
GO:0005856
GO:0005874
GO:0005886
GO:0005911
GO:0006351
GO:0006355
GO:0006468
GO:0009898
GO:0010628
GO:0016301
GO:0016310
GO:0016740
GO:0023052
GO:0030165
GO:0036211
GO:0043226
GO:0043410
GO:0043539
GO:0045893
GO:0048471
GO:0060090
GO:0070371
GO:0097110
GO:0098772
GO:0140096
Ssc.30855.1.S1_at
Ssc.3466.1.S1_at
Participates
as a component of
p-S222,S226 MAP2K2 dimer [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-p-S,T-MAP2K2 [cytosol]
MAP2K2 [cytosol]
Inferred From
p-S222,S226-MAP2K2 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 222 (in Homo sapiens)
Coordinate
222
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 226 (in Homo sapiens)
Coordinate
226
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_001231479.1
Ensembl
ENSSSCG00000027127
,
ENSSSCP00000029885
,
ENSSSCT00000035211
VGNC
100166
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