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MAPK8 [cytosol]
Stable Identifier
R-SSC-168141
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
MAPK8, K7GRS5
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular Senescence (Sus scrofa)
Oxidative Stress Induced Senescence (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Immune System (Sus scrofa)
Cytokine Signaling in Immune system (Sus scrofa)
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-38 signaling (Sus scrofa)
MAPK8 phosphorylation (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Interleukin-17 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Innate Immune System (Sus scrofa)
Fc epsilon receptor (FCERI) signaling (Sus scrofa)
FCERI mediated MAPK activation (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
MAPK8,9,10 [cytosol] (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Programmed Cell Death (Sus scrofa)
Apoptosis (Sus scrofa)
Intrinsic Pathway for Apoptosis (Sus scrofa)
Activation of BH3-only proteins (Sus scrofa)
Activation of BIM and translocation to mitochondria (Sus scrofa)
Phosphorylation of BIM by JNK (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Activation of BMF and translocation to mitochondria (Sus scrofa)
Phosphorylation of DLC2 by MAPK8 (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Death Receptor Signaling (Sus scrofa)
p75 NTR receptor-mediated signalling (Sus scrofa)
Cell death signalling via NRAGE, NRIF and NADE (Sus scrofa)
NRAGE signals death through JNK (Sus scrofa)
GTP-bound RAC contributes to JNK activation (Sus scrofa)
MAPK8 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:K7GRS5
Gene Names
MAPK8
Reference Genes
BioGPS Gene:396610 MAPK8
ENSEMBL:ENSSSCG00000010380.6
Monarch:396610 MAPK8
NCBI Gene:396610 MAPK8
Reference Transcript
RefSeq:XM_003359272.3 MAPK8
Other Identifiers
396610
GO:0000165
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004705
GO:0004707
GO:0005524
GO:0005634
GO:0005737
GO:0006468
GO:0006979
GO:0007254
GO:0009411
GO:0010628
GO:0012501
GO:0016301
GO:0016310
GO:0016740
GO:0019899
GO:0019903
GO:0023052
GO:0032880
GO:0034198
GO:0034599
GO:0034614
GO:0035033
GO:0036211
GO:0042826
GO:0043066
GO:0043226
GO:0048511
GO:0051247
GO:0051403
GO:0065003
GO:0071222
GO:0071260
GO:0071276
GO:0098772
GO:0106310
GO:0120283
GO:0140096
GO:1900227
Ssc.19706.1.S1_at
Ssc.21418.2.A1_at
Ssc.23860.1.A1_at
Participates
as an input of
GTP-bound RAC contributes to JNK activation (Sus scrofa)
MAPK8 phosphorylation (Sus scrofa)
as a member of
MAPK8,9,10 [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-MAPK8 [cytosol]
phospho-MAPK8 [nucleoplasm]
Inferred From
MAPK8 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_003359320.1
OpenTargets
ENSG00000107643
Ensembl
ENSSSCP00000030604
,
ENSSSCG00000010380
,
ENSSSCT00000036610
VGNC
90006
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