Reactome | CCNE1 [cytosol]

CCNE1 [cytosol]

Stable Identifier

R-SSC-157443

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

CCNE1, F1RNY7

Locations in the PathwayBrowser

Expand all

Cell Cycle (Sus scrofa)

- Cell Cycle, Mitotic (Sus scrofa)
  - Mitotic G1 phase and G1/S transition (Sus scrofa)
    - G1/S Transition (Sus scrofa)
      - Cyclin E associated events during G1/S transition (Sus scrofa)
        
        Formation of Cyclin E:Cdk2 complexes (Sus scrofa)
        
        CCNE [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        CCNE:CDK2 [cytosol] (Sus scrofa)
        
        CCNE [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        SCF(Skp2)-mediated degradation of p27/p21 (Sus scrofa)
        
        Activated PTK6 binds CDKN1B (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        PTK6 phosphorylates CDKN1B (Sus scrofa)
        
        p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        p-Y88-CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        Translocation of Cyclin E:Cdk2 complex to the nucleus (Sus scrofa)
        
        CCNE:CDK2 [cytosol] (Sus scrofa)
        
        CCNE [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
  - S Phase (Sus scrofa)
    - Cyclin A:Cdk2-associated events at S phase entry (Sus scrofa)
      - SCF(Skp2)-mediated degradation of p27/p21 (Sus scrofa)
        
        Activated PTK6 binds CDKN1B (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        PTK6 phosphorylates CDKN1B (Sus scrofa)
        
        p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        p-Y88-CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)

Signal Transduction (Sus scrofa)

- Signaling by Non-Receptor Tyrosine Kinases (Sus scrofa)
  - Signaling by PTK6 (Sus scrofa)
    - PTK6 Regulates Cell Cycle (Sus scrofa)
      - Activated PTK6 binds CDKN1B (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
      - PTK6 phosphorylates CDKN1B (Sus scrofa)
        
        p-Y342-PTK6:CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)
        
        p-Y88-CDKN1B:(CDK4:CCND1,(CDK2:CCNE1)) [cytosol] (Sus scrofa)
        
        CCND1:CDK4,(CCNE1:CDK2) [cytosol] (Sus scrofa)
        
        Cyclin E1:CDK2 [cytosol] (Sus scrofa)
        
        CCNE1 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1RNY7

Gene Names

CCNE1

Reference Genes

ENSEMBL:ENSSSCG00000002855.5

Other Identifiers

100523248

GO:0000082

GO:0000122

GO:0000278

GO:0000307

GO:0000723

GO:0003824

GO:0005634

GO:0005654

GO:0005737

GO:0005813

GO:0005815

GO:0005856

GO:0006260

GO:0006270

GO:0006351

GO:0006355

GO:0007059

GO:0007129

GO:0016055

GO:0016301

GO:0016538

GO:0016740

GO:0019901

GO:0022414

GO:0023052

GO:0032200

GO:0032880

GO:0043226

GO:0051726

GO:0070192

GO:0097134

GO:0098772

GO:0140013

GO:1902462

Ssc.18187.1.A1_at

Ssc.18187.2.S1_at

Participates

as a component of

Cyclin E1:CDK2 [cytosol] (Sus scrofa)

as a member of

CCNE [cytosol] (Sus scrofa)

Other forms of this molecule

CCNE1 [nucleoplasm]

Inferred From

CCNE1 [cytosol] (Homo sapiens)

Cross References

OpenTargets

ENSG00000105173

Ensembl

ENSSSCP00000003075, ENSSSCG00000002855, ENSSSCT00000003156

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