Reactome | phospho-p-S19,S23-Ub-NFKBIB [cytosol]

phospho-p-S19,S23-Ub-NFKBIB [cytosol]

Stable Identifier

R-SSC-1168571

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

I3LLS5

Locations in the PathwayBrowser

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Immune System (Sus scrofa)

- Adaptive Immune System (Sus scrofa)
  - Signaling by the B Cell Receptor (BCR) (Sus scrofa)
    - Downstream signaling events of B Cell Receptor (BCR) (Sus scrofa)
      - Activation of NF-kappaB in B cells (Sus scrofa)
        
        Ubiquitinated IkB is degraded (Sus scrofa)
        
        NF-kappaB p50,p65,c-Rel:ub-p-IKB [cytosol] (Sus scrofa)
        
        NF-kappaB p50:c-Rel:ub-p-IKB [cytosol] (Sus scrofa)
        
        ub-p-IKB alpha,beta,epsilon [cytosol] (Sus scrofa)
        
        phospho-p-S19,S23-Ub-NFKBIB [cytosol] (Sus scrofa)
        
        NF-kappaB p50:p65:ub-p-IKB [cytosol] (Sus scrofa)
        
        ub-p-IKB alpha,beta,epsilon [cytosol] (Sus scrofa)
        
        phospho-p-S19,S23-Ub-NFKBIB [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:I3LLS5

Reference Genes

BioGPS Gene:100621111

ENSEMBL:ENSSSCG00000026904.4

ENSEMBL:ENSSSCG00005044163.1

KEGG Gene (Sus scrofa):100621111

Monarch:100621111

NCBI Gene:100621111

Reference Transcript

RefSeq:XM_003355897.4

Other Identifiers

100621111

GO:0005515

GO:0006954

GO:0023052

GO:0043122

GO:0071222

Ssc.28384.1.A1_at

Participates

as a member of

ub-p-IKB alpha,beta,epsilon [cytosol] (Sus scrofa)

Other forms of this molecule

phospho-p-S19,S23-NFKBIB [cytosol]

NFKBIB [cytosol]

Inferred From

p-S19,S23-Ub-NFKBIB [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 19 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

O-phospho-L-serine at 23 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Name

ubiquitinylated lysine (K48polyUb [cytosol]) at unknown position

Modification

K48polyUb [cytosol]

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

XP_003355945.2

Ensembl

ENSSSCG00000026904, ENSSSCP00000025045, ENSSSCT00000025426

VGNC

90722

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