Reactome | rpl26 [cytosol]

rpl26 [cytosol]

Stable Identifier

R-SPO-72436

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Synonyms

RPL26, P78946

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Schizosaccharomyces pombe)

- Nonsense-Mediated Decay (NMD) (Schizosaccharomyces pombe)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Schizosaccharomyces pombe)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        rpl26 [cytosol] (Schizosaccharomyces pombe)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        rpl26 [cytosol] (Schizosaccharomyces pombe)
    - SMG6 hydrolyzes mRNA with premature termination codon (Schizosaccharomyces pombe)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        rpl26 [cytosol] (Schizosaccharomyces pombe)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Schizosaccharomyces pombe)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        rpl26 [cytosol] (Schizosaccharomyces pombe)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Schizosaccharomyces pombe)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Schizosaccharomyces pombe)
        
        80S ribosome [cytosol] (Schizosaccharomyces pombe)
        
        60S ribosomal complex [cytosol] (Schizosaccharomyces pombe)
        
        rpl26 [cytosol] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:P78946

Gene Names

rpl26

Reference Genes

BioGPS Gene:2540274 rpl26

ENSEMBL:SPBC29B5.03c

GeneDB:SPBC29B5.03c

KEGG Gene (Schizosaccharomyces pombe):SPBC29B5.03c rpl26

Monarch:2540274 rpl26

NCBI Gene:2540274 rpl26

Reference Transcript

RefSeq:NM_001021548.2 rpl26

Participates

as a component of

Inferred From

RPL26,RPL26L1 [cytosol] (Homo sapiens)

RPL26 [cytosol] (Homo sapiens)

RPL26L1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_595654.1

PRO

P78946

PDB

8ESR, 8ESQ, 8ETJ, 8EUI, 8EUY, 8EUG, 8EV3, 8ETG, 8ETC, 8ETI, 8ETH, 8EUP

Cite Us!