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MCM5 [nucleoplasm]
Stable Identifier
R-SPO-68551
Type
Protein [EntityWithAccessionedSequence]
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Synonyms
P41389
Locations in the PathwayBrowser
Expand all
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle Checkpoints (Schizosaccharomyces pombe)
G2/M Checkpoints (Schizosaccharomyces pombe)
Activation of ATR in response to replication stress (Schizosaccharomyces pombe)
Loading of claspin onto DNA during replication origin firing (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Cdc45:CDK:DDK:Mcm10:claspin:pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Cell Cycle, Mitotic (Schizosaccharomyces pombe)
Mitotic G1 phase and G1/S transition (Schizosaccharomyces pombe)
G1/S Transition (Schizosaccharomyces pombe)
Activation of the pre-replicative complex (Schizosaccharomyces pombe)
CDK and DDK associate with the Mcm10:pre-replicative complex (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Cdc45 associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Cdt1 is displaced from the pre-replicative complex. (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase alpha:primase binds at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase epsilon binds at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Schizosaccharomyces pombe)
MCM10:pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Mcm2-7 is phosphorylated by DDK (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
p-MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
S Phase (Schizosaccharomyces pombe)
Synthesis of DNA (Schizosaccharomyces pombe)
Switching of origins to a post-replicative state (Schizosaccharomyces pombe)
Mcm4,6,7 trimer forms and associates with the replication fork (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Orc1 removal from chromatin (Schizosaccharomyces pombe)
Orc1 is phosphorylated by cyclin A/CDK2 (Schizosaccharomyces pombe)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
DNA Replication (Schizosaccharomyces pombe)
DNA Replication Pre-Initiation (Schizosaccharomyces pombe)
Activation of the pre-replicative complex (Schizosaccharomyces pombe)
CDK and DDK associate with the Mcm10:pre-replicative complex (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Cdc45 associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Cdt1 is displaced from the pre-replicative complex. (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase alpha:primase binds at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase epsilon binds at the origin (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Schizosaccharomyces pombe)
CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM10:active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
active pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Schizosaccharomyces pombe)
MCM10:pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Mcm2-7 is phosphorylated by DDK (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
p-MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Assembly of the pre-replicative complex (Schizosaccharomyces pombe)
Formation of MCM2-7 complex (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3 binds MCM5 (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Synthesis of DNA (Schizosaccharomyces pombe)
Switching of origins to a post-replicative state (Schizosaccharomyces pombe)
Mcm4,6,7 trimer forms and associates with the replication fork (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Orc1 removal from chromatin (Schizosaccharomyces pombe)
Orc1 is phosphorylated by cyclin A/CDK2 (Schizosaccharomyces pombe)
pre-replicative complex (Orc1-minus) [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
pre-replicative complex [nucleoplasm] (Schizosaccharomyces pombe)
MCM2-7 [nucleoplasm] (Schizosaccharomyces pombe)
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
External Reference Information
External Reference
UniProt:P41389
Reference Genes
ENSEMBL:SPAC1B2.05
GeneDB:SPAC1B2.05
Participates
as an output of
Mcm4,6,7 trimer forms and associates with the replication fork (Schizosaccharomyces pombe)
as an input of
MCM3 binds MCM5 (Schizosaccharomyces pombe)
as a component of
MCM3:MCM5 [nucleoplasm] (Schizosaccharomyces pombe)
Inferred From
MCM5 [nucleoplasm]
(Homo sapiens)
Cross References
IntEnz
3.6.4.12
PRO
P41389
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O94450 YFF4
0.499
2
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