Reactome | BUB1B [cytosol]

BUB1B [cytosol]

Stable Identifier

R-SPO-141436

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

cytosol

Synonyms

O94751

Locations in the PathwayBrowser

Expand all

Cell Cycle (Schizosaccharomyces pombe)

- Cell Cycle Checkpoints (Schizosaccharomyces pombe)
  - Mitotic Spindle Checkpoint (Schizosaccharomyces pombe)
    - Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Schizosaccharomyces pombe)
      - Inactivation of APC/C via direct inhibition of the APC/C complex (Schizosaccharomyces pombe)
        
        Formation of the MCC complex (Schizosaccharomyces pombe)
        
        BUB1B [cytosol] (Schizosaccharomyces pombe)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Schizosaccharomyces pombe)
        
        BUB1B [cytosol] (Schizosaccharomyces pombe)
- Cell Cycle, Mitotic (Schizosaccharomyces pombe)
  - Regulation of mitotic cell cycle (Schizosaccharomyces pombe)
    - APC/C-mediated degradation of cell cycle proteins (Schizosaccharomyces pombe)
      - Regulation of APC/C activators between G1/S and early anaphase (Schizosaccharomyces pombe)
        
        Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Schizosaccharomyces pombe)
        
        Inactivation of APC/C via direct inhibition of the APC/C complex (Schizosaccharomyces pombe)
        
        Formation of the MCC complex (Schizosaccharomyces pombe)
        
        BUB1B [cytosol] (Schizosaccharomyces pombe)
        
        hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Schizosaccharomyces pombe)
        
        BUB1B [cytosol] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:O94751

Reference Genes

BioGPS Gene:2538736

ENSEMBL:SPCC1322.12c

GeneDB:SPCC1322.12c

KEGG Gene (Schizosaccharomyces pombe):SPCC1322.12c

Monarch:2538736

NCBI Gene:2538736

Reference Transcript

RefSeq:NM_001023130.2

Participates

as an input of

Formation of the MCC complex (Schizosaccharomyces pombe)

as a component of

hBUBR1:hBUB3:MAD2*:CDC20 complex [cytosol] (Schizosaccharomyces pombe)

Inferred From

BUB1B [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_588140.1

PRO

O94751

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O94751	1	BUB1B [cytosol] (R-SPO-141436)	0.592	2

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