Reactome | Me3K318-EEF1A1 [cytosol]

Me3K318-EEF1A1 [cytosol]

Stable Identifier

R-SCE-8932419

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

P02994

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P02994

Reference Genes

BioGPS Gene:852415

BioGPS Gene:856195

ENSEMBL:YBR118W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YBR118W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YPR080W

Monarch:852415

Monarch:856195

NCBI Gene:852415

NCBI Gene:856195

SGD:YBR118W

Reference Transcript

Other Identifiers

1F60

1G7C

1IJE

1IJF

2B7B

2B7C

4932.YPR080W

5O8W

AAA34584.1

AAA34585.1

AAA34586.1

AAB68129.1

AAM83111.1

AAM83112.1

AAM83113.1

AAM83114.1

AAP86465.1

AAT92946.1

CAA25356.1

CAA25798.1

CAA51936.1

CAA55620.1

CAA85075.1

DAA07236.1

DAA11498.1

EntrezGene:852415

EntrezGene:856195

GO:0000329

GO:0001933

GO:0003674

GO:0003723

GO:0003746

GO:0003779

GO:0003924

GO:0005525

GO:0005575

GO:0005737

GO:0005739

GO:0005773

GO:0005840

GO:0005853

GO:0005856

GO:0006409

GO:0006414

GO:0006468

GO:0006469

GO:0008092

GO:0008135

GO:0008150

GO:0015031

GO:0015931

GO:0016020

GO:0016787

GO:0019003

GO:0019899

GO:0019901

GO:0031399

GO:0034198

GO:0042594

GO:0043022

GO:0043167

GO:0051169

IPR000795

IPR004160

IPR004161

IPR004539

IPR009000

IPR009001

IPR027417

IPR031157

NM_001178466.1

NM_001184177.1

NP_009676.1

NP_015405.1

PF00009

PF03143

PF03144

PR00315

UPI0000053080

YBR118W

YBR118W_mRNA

YPR080W

YPR080W_mRNA

Participant Of

output

METTL10 transfers 3xCH3 from 3xAdoMet to EEF1A1

Other forms of this molecule

EEF1A1 [cytosol]

EEF1A1 [ficolin-1-rich granule lumen]

EEF1A1 [extracellular region]

EEF1A1 [secretory granule lumen]

Me3K79-EEF1A1 [cytosol]

Inferred From

Me3K318-EEF1A1 [cytosol] (Homo sapiens)

Modified Residues

Name

N6,N6,N6-trimethyl-L-lysine at 318 (in Homo sapiens)

Coordinate

318

PsiMod Name

N6,N6,N6-trimethyl-L-lysine [MOD:00083]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine.

Cross References

RefSeq

NP_015405.1, NP_009676.1

PRO

P02994

PDB

1G7C, 1F60, 5O8W, 1IJE, 2B7C, 2B7B, 1IJF

Interactors (41)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32471	2	EEF1D [cytosol] (R-SCE-156914) EEF1B2 [cytosol] (R-SCE-156926)	0.731	4
UniProt:P17555	2	CAP1 [azurophil granule lumen] (R-SCE-6798752) CAP1 [extracellular region] (R-SCE-350746)	0.576	3
UniProt:P35845	1	OSBP [cytosol] (R-SCE-429725)	0.564	2
UniProt:P00817	2	PPA1 [cytosol] (R-SCE-71725) PPA2 [mitochondrial matrix] (R-SCE-449918)	0.564	2
UniProt:P10662 RT01			0.564	2
UniProt:Q62384 ZPR1			0.558	2
UniProt:P16862	5	PFKL [extracellular region] (R-SCE-6806471-2) PFKL [secretory granule lumen] (R-SCE-6800876-2) PFKL [ficolin-1-rich granule lumen] (R-SCE-6801030-2) PFKP [cytosol] (R-SCE-71452-2) PFKL [cytosol] (R-SCE-70459-2)	0.527	2
UniProt:P40991 NOP2	1	NOP2 [nucleoplasm] (R-SCE-6790926)	0.527	2
UniProt:P15992 HSP26			0.527	2
UniProt:P39743 RV167			0.527	3
UniProt:P40354 NTA1			0.527	2
UniProt:Q00362	2	PPP2R2A [nucleoplasm] (R-SCE-1564978) PPP2R2A [cytosol] (R-SCE-377253)	0.527	3
UniProt:Q01477	3	USP37 [nucleoplasm] (R-SCE-5697000) USP10 [nucleoplasm] (R-SCE-3222218) USP10 [cytosol] (R-SCE-6782974)	0.527	2
UniProt:Q05022 RRP5	2	PDCD11 [nucleoplasm] (R-SCE-6790646) RRP5 [nucleoplasm] (R-SCE-6790686)	0.527	2
UniProt:Q12329 HSP42			0.527	2
UniProt:P38080 AKL1			0.527	2
UniProt:P25694	7	VCP [ficolin-1-rich granule lumen] (R-SCE-6800425) VCP [cytosol] (R-SCE-1181251) VCP [extracellular region] (R-SCE-6806191) VCP [secretory granule lumen] (R-SCE-6801039) VCP [azurophil granule lumen] (R-SCE-6800438) VCP [nucleoplasm] (R-SCE-5643745) Me3K315-VCP [cytosol] (R-SCE-8932209)	0.527	2
UniProt:P53883 NOP13			0.527	3
UniProt:P04819	1	LIG1 [nucleoplasm] (R-SCE-53787)	0.527	2
UniProt:P20484 MAK11			0.527	2
UniProt:P25454	2	phospho-p-T309-RAD51 [nucleoplasm] (R-SCE-5685231) RAD51 [nucleoplasm] (R-SCE-62637)	0.527	2
UniProt:P35191 MDJ1			0.527	2
UniProt:P40469 MET18	1	MET18 [cytosol] (R-SCE-2564782)	0.527	2
UniProt:Q03768 GIR2			0.527	2
UniProt:P10591	23	HSPA8 [nucleoplasm] (R-SCE-5082380-2) HSPA8 [cytosol] (R-SCE-264476-2) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-2) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-2) HSPA8 [ficolin-1-rich granule lumen] (R-SCE-6801494-2) HSPA1A [extracellular region] (R-SCE-6805872-2) HSPA6 [extracellular region] (R-SCE-6806500-2) HSPA8 [extracellular region] (R-SCE-6805936-2) HSPA8 [secretory granule lumen] (R-SCE-6801530-2) HSPA6 [secretory granule lumen] (R-SCE-6801472-2) HSPA2 [nucleoplasm] (R-SCE-912480-2) HSPA1L [nucleoplasm] (R-SCE-5082367-2) HSPA1A [nucleoplasm] (R-SCE-6792605-2) HSPA6 [nucleoplasm] (R-SCE-5252088-2) HSPA13 [nucleoplasm] (R-SCE-5252009-2) HSPA7 [nucleoplasm] (R-SCE-5252047-2) HSPA1L [cytosol] (R-SCE-3371410-2) HSPA2 [cytosol] (R-SCE-3371408-2) HSPA13 [cytosol] (R-SCE-5251981-2) HSPA6 [cytosol] (R-SCE-3371521-2) HSPA7 [cytosol] (R-SCE-5251954-2) HSPA1A [cytosol] (R-SCE-6792602-2) Me3K561-HSPA8 [nucleoplasm] (R-SCE-8932217-2)	0.527	2
UniProt:P10592	23	HSPA8 [nucleoplasm] (R-SCE-5082380-3) HSPA8 [cytosol] (R-SCE-264476-3) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-3) HSPA8 [ficolin-1-rich granule lumen] (R-SCE-6801494-3) HSPA1A [extracellular region] (R-SCE-6805872-3) HSPA6 [extracellular region] (R-SCE-6806500-3) HSPA8 [extracellular region] (R-SCE-6805936-3) HSPA8 [secretory granule lumen] (R-SCE-6801530-3) HSPA6 [secretory granule lumen] (R-SCE-6801472-3) HSPA2 [nucleoplasm] (R-SCE-912480-3) HSPA1L [nucleoplasm] (R-SCE-5082367-3) HSPA1A [nucleoplasm] (R-SCE-6792605-3) HSPA6 [nucleoplasm] (R-SCE-5252088-3) HSPA13 [nucleoplasm] (R-SCE-5252009-3) HSPA7 [nucleoplasm] (R-SCE-5252047-3) HSPA1L [cytosol] (R-SCE-3371410-3) HSPA2 [cytosol] (R-SCE-3371408-3) HSPA13 [cytosol] (R-SCE-5251981-3) HSPA6 [cytosol] (R-SCE-3371521-3) HSPA7 [cytosol] (R-SCE-5251954-3) HSPA1A [cytosol] (R-SCE-6792602-3) Me3K561-HSPA8 [nucleoplasm] (R-SCE-8932217-3)	0.527	2
UniProt:P33892 GCN1	1	GCN1 [cytosol] (R-SCE-9633502)	0.527	2
UniProt:P11484	23	HSPA8 [nucleoplasm] (R-SCE-5082380-4) HSPA8 [cytosol] (R-SCE-264476-4) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA8 [ficolin-1-rich granule lumen] (R-SCE-6801494-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA8 [extracellular region] (R-SCE-6805936-4) HSPA8 [secretory granule lumen] (R-SCE-6801530-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA7 [nucleoplasm] (R-SCE-5252047-4) HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4) HSPA7 [cytosol] (R-SCE-5251954-4) HSPA1A [cytosol] (R-SCE-6792602-4) Me3K561-HSPA8 [nucleoplasm] (R-SCE-8932217-4)	0.527	3
UniProt:P38720	1	PGD [cytosol] (R-SCE-71297)	0.527	2
UniProt:Q12055	1	AK6 [nucleoplasm] (R-SCE-6788786)	0.527	2
UniProt:P25303 SCJ1			0.527	2
UniProt:P39081	1	PCF11 [nucleoplasm] (R-SCE-72019)	0.527	2
UniProt:Q08004 BUD20			0.527	3
UniProt:P20081 FKBP			0.527	2
UniProt:P32589	5	HSPA4 [cytosol] (R-SCE-5251946) HSPH1 [cytosol] (R-SCE-3299412) HSPA4L [cytosol] (R-SCE-5251943) HSPA4 [nucleoplasm] (R-SCE-5251998) HSPA4L [nucleoplasm] (R-SCE-5252053)	0.527	3
UniProt:P32601 DSS4			0.527	2
UniProt:P32345 PP4C			0.527	2
UniProt:P32585 MED18			0.527	2
UniProt:P15442 GCN2	2	p-T882,887-GCN2 [cytosol] (R-SCE-9633799) GCN2 [cytosol] (R-SCE-9633552)	0.527	2
UniProt:P43573 BUD27			0.508	2
UniProt:Q05040	1	STRN [cytosol] (R-SCE-9037081)	0.499	2