Reactome | phospho-p-T210-PLK1 [cytosol]

phospho-p-T210-PLK1 [cytosol]

Stable Identifier

R-SCE-3000318

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

P32562

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P32562

Reference Genes

BioGPS Gene:855013

dbSNP Gene:855013

ENSEMBL:YMR001C

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YMR001C

Monarch:855013

NCBI Gene:855013

SGD:YMR001C

Reference Transcript

RefSeq:NM_001182497.1

Other Identifiers

1775593_at

4932.YMR001C

9623_at

CAA88516.1

DAA09899.1

EntrezGene:855013

EntrezGene:CDC5

GO:0000278

GO:0000712

GO:0000922

GO:0003674

GO:0003677

GO:0004672

GO:0004674

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005856

GO:0005933

GO:0005935

GO:0006310

GO:0006468

GO:0006997

GO:0007010

GO:0007059

GO:0008047

GO:0008104

GO:0008150

GO:0010458

GO:0010696

GO:0016301

GO:0016740

GO:0019237

GO:0030234

GO:0030427

GO:0032403

GO:0033043

GO:0043167

GO:0048285

GO:0051219

GO:0051301

GO:0051321

GO:0051726

GO:0070194

GO:0070925

GO:0090306

GO:1902542

GO:1903353

IPR000719

IPR000959

IPR008271

IPR011009

IPR017441

IPR033695

IPR033701

IPR036947

M84220

NM_001182497.1

NP_013714.1

PF00069

PF00659

SM00220

UPI0000127258

YMR001C

YMR001C_mRNA

Participant Of

hasComponent

input

Cytosolic PLK1 translocates to the nucleus

Other forms of this molecule

PLK1 [nucleoplasm]

phospho-p-T210-PLK1 [nucleoplasm]

PLK3 [nucleoplasm]

PLK1 [cytosol]

Inferred From

p-T210-PLK1 [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 210 (in Homo sapiens)

Coordinate

210

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_013714.1

PRO

P32562

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32908	4	SMC1A [chromosome] (R-SCE-1638774) SMC1A [cytosol] (R-SCE-2484798) SMC1A [chromosome, centromeric region] (R-SCE-2466015) SMC1A [nucleoplasm] (R-SCE-64561)	0.643	3
UniProt:P47037	6	2xAcK-SMC3 [cytosol] (R-SCE-2484792) SMC3 [cytosol] (R-SCE-2545223) 2xAcK-SMC3 [chromosome] (R-SCE-2468146) SMC3 [nucleoplasm] (R-SCE-163009) 2xAcK-SMC3 [chromosome, centromeric region] (R-SCE-2468148) 2xAcK-SMC3 [nucleoplasm] (R-SCE-2468050)	0.643	3
UniProt:P32944	2	PKMYT1 [nucleoplasm] (R-SCE-74386) phospho-p-PKMYT1 [nucleoplasm] (R-SCE-162650)	0.635	4
UniProt:P06243	1	CDC7 [nucleoplasm] (R-SCE-51781)	0.558	11
UniProt:P41813 FKH2			0.558	2
UniProt:Q96M27 PRRC1			0.556	3
UniProt:P14859-6 POU2F1			0.556	3
UniProt:Q13422-7 IKZF1			0.556	3
UniProt:Q7L5A3 F214B			0.556	3
UniProt:P63279 UBE2I	8	SUMO1-C93-UBE2I [cytosol] (R-HSA-4656909) SUMO1-K14-UBE2I [nucleoplasm] (R-HSA-4085358) UBE2I [nuclear envelope] (R-HSA-4655408) UBE2I [cytosol] (R-HSA-4655342) SUMO3-C93-UBE2I [nucleoplasm] (R-HSA-3730629) SUMO2-C93-UBE2I [nucleoplasm] (R-HSA-3730619) UBE2I [nucleoplasm] (R-HSA-912481) SUMO1-C93-UBE2I [nucleoplasm] (R-HSA-3730617)	0.556	3
UniProt:P22216 RAD53			0.544	3
UniProt:Q04934 IVY1			0.527	2
UniProt:P40541	11	STAG2 [cytosol] (R-SCE-2484897) SUMO1-K-STAG2 [nucleoplasm] (R-SCE-3108187) STAG1 [cytosol] (R-SCE-2484793) phospho-p-STAG2 [cytosol] (R-SCE-2484806) phospho-p-STAG2 [chromosome] (R-SCE-1638793) STAG1 [chromosome] (R-SCE-1638773) STAG2 [chromosome] (R-SCE-1638777) STAG2 [chromosome, centromeric region] (R-SCE-2466018) STAG1 [chromosome, centromeric region] (R-SCE-2466017) STAG1 [nucleoplasm] (R-SCE-163016) STAG2 [nucleoplasm] (R-SCE-163046)	0.527	2
UniProt:Q02821	2	KPNA2 [cytosol] (R-SCE-205976) KPNA1 [cytosol] (R-SCE-180612)	0.527	2
UniProt:Q06142	4	KPNB1 [extracellular region] (R-SCE-6806306) KPNB1 [specific granule lumen] (R-SCE-6799646) KPNB1 [ficolin-1-rich granule lumen] (R-SCE-6800978) KPNB1 [cytosol] (R-SCE-180733)	0.527	2
UniProt:Q12158	10	RAD21 [cytosol] (R-SCE-2484795) SUMO1-K-RAD21 [nucleoplasm] (R-SCE-3108183) phospho-p-S454-RAD21(451-631) [cytosol] (R-SCE-2500309) RAD21(173-450) [cytosol] (R-SCE-2500308) RAD21(1-172) [cytosol] (R-SCE-2484901) phospho-p-S454-RAD21 [cytosol] (R-SCE-2500310) phospho-p-S454-RAD21 [chromosome] (R-SCE-2485164) RAD21 [chromosome] (R-SCE-1638775) RAD21 [chromosome, centromeric region] (R-SCE-2466012) RAD21 [nucleoplasm] (R-SCE-163042)	0.527	2
UniProt:Q00684	1	CDC14A [cytosol] (R-SCE-174094)	0.524	2
UniProt:P23624 SPO13			0.499	8
UniProt:P14737	2	TP53BP1 [nucleoplasm] (R-SCE-61175) SUMO1-K-TP53BP1 [nucleoplasm] (R-SCE-2997591)	0.499	2
UniProt:P32325	1	DBF4 [nucleoplasm] (R-SCE-68387)	0.462	3