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phospho-p-T308,S473-AKT1 [cytosol]
Stable Identifier
R-SCE-198356
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
P11792
Locations in the PathwayBrowser
Expand all
Immune System (Saccharomyces cerevisiae)
Adaptive Immune System (Saccharomyces cerevisiae)
Costimulation by the CD28 family (Saccharomyces cerevisiae)
CD28 co-stimulation (Saccharomyces cerevisiae)
CD28 dependent PI3K/Akt signaling (Saccharomyces cerevisiae)
AKT interacts and phosphorylates Cot (Saccharomyces cerevisiae)
p-T,p-S-AKT [cytosol] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
CTLA4 inhibitory signaling (Saccharomyces cerevisiae)
Dephosphorylation of AKT by PP2A (Saccharomyces cerevisiae)
p-T,p-S-AKT [cytosol] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
Metabolism (Saccharomyces cerevisiae)
Metabolism of nitric oxide: NOS3 activation and regulation (Saccharomyces cerevisiae)
eNOS activation (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
BH2 binding can lead to eNOS uncoupling (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
Uncoupled eNOS favours the formation of superoxide (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of cofactors (Saccharomyces cerevisiae)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Saccharomyces cerevisiae)
BH2 binding can lead to eNOS uncoupling (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
Metabolism of RNA (Saccharomyces cerevisiae)
Regulation of mRNA stability by proteins that bind AU-rich elements (Saccharomyces cerevisiae)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Saccharomyces cerevisiae)
Protein Kinase B/Akt phosphorylates BRF1 (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
Signal Transduction (Saccharomyces cerevisiae)
Intracellular signaling by second messengers (Saccharomyces cerevisiae)
PIP3 activates AKT signaling (Saccharomyces cerevisiae)
Negative regulation of the PI3K/AKT network (Saccharomyces cerevisiae)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Saccharomyces cerevisiae)
AKT1 dephosphorylation by PP2A-B56-beta,gamma (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
Signaling by Nuclear Receptors (Saccharomyces cerevisiae)
ESR-mediated signaling (Saccharomyces cerevisiae)
Extra-nuclear estrogen signaling (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
Signaling by Receptor Tyrosine Kinases (Saccharomyces cerevisiae)
Signaling by VEGF (Saccharomyces cerevisiae)
VEGFA-VEGFR2 Pathway (Saccharomyces cerevisiae)
VEGFR2 mediated vascular permeability (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
phospho-p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P11792
Reference Genes
BioGPS Gene:856612
ENSEMBL:YHR205W
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YHR205W
Monarch:856612
NCBI Gene:856612
SGD:YHR205W
Reference Transcript
RefSeq:NM_001179336.1
Other Identifiers
1776699_at
4318_at
856612
GO:0000166
GO:0000329
GO:0000785
GO:0001302
GO:0001324
GO:0003674
GO:0004672
GO:0004674
GO:0005524
GO:0005575
GO:0005634
GO:0005694
GO:0005737
GO:0005773
GO:0006357
GO:0006360
GO:0006366
GO:0006383
GO:0006468
GO:0006520
GO:0006629
GO:0006970
GO:0006979
GO:0008150
GO:0008361
GO:0016020
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0018193
GO:0023052
GO:0032880
GO:0035556
GO:0042221
GO:0043167
GO:0043619
GO:0045943
GO:0045945
GO:0047484
GO:0060963
GO:0090153
GO:0106310
GO:1901494
GO:1904828
Participates
as a member of
Homologues of p-T308,S473-AKT1 [cytosol] (Saccharomyces cerevisiae)
Other forms of this molecule
phospho-p-T308,S473-AKT1 [plasma membrane]
phospho-p-T308-AKT1 [cytosol]
phospho-p-T305-AKT3 [cytosol]
phospho-p-T309-AKT2 [cytosol]
SGK1 [cytosol]
phospho-p-S422-SGK1 [cytosol]
phospho-p-T256,S422-SGK1 [cytosol]
phospho-p-T256,S422-SGK1 [nucleoplasm]
AKT1 [cytosol]
AKT3 [cytosol]
AKT2 [cytosol]
AKT1 [plasma membrane]
AKT3 [plasma membrane]
AKT2 [plasma membrane]
phospho-p-S473-AKT1 [plasma membrane]
phospho-p-S472-AKT3 [plasma membrane]
phospho-p-S474-AKT2 [plasma membrane]
phospho-p-T309,S474-AKT2 [cytosol]
phospho-p-T305,S472-AKT3 [cytosol]
phospho-p-T308,S473-AKT1 [nucleoplasm]
phospho-p-T305,S472-AKT3 [nucleoplasm]
phospho-p-T309,S474-AKT2 [nucleoplasm]
Inferred From
p-T308,S473-AKT1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 308 (in Homo sapiens)
Coordinate
308
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O-phospho-L-serine at 473 (in Homo sapiens)
Coordinate
473
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_012075.1
PRO
P11792
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