Reactome | Fbxo44 [cytosol]

Fbxo44 [cytosol]

Stable Identifier

R-RNO-976031

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

FBXO44, D4A6R1

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Rattus norvegicus)

- Post-translational protein modification (Rattus norvegicus)
  - Neddylation (Rattus norvegicus)
    - AcM-UBE2M transfers NEDD8 to CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)
      - CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Rattus norvegicus)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
      - NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
      - NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Rattus norvegicus)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Rattus norvegicus)
        
        CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
      - CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Rattus norvegicus)
        
        CRL E3 ubiquitin ligases [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Rattus norvegicus)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        NEDD8-CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        NEDD8-CRL1 E3 ligase complex [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
    - MyrG-DCUN1D3 binds CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)
      - CRL1 E3 ubiquitin ligase complex:MyrG-DCUN1D3 [plasma membrane] (Rattus norvegicus)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
      - CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
    - NEDD8:AcM-UBE2M binds CRL1 E3 ubiquitin ligase complex (Rattus norvegicus)
      - CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)
      - NEDD8-AcM-UBE2M:CRL1 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Rattus norvegicus)
        
        CRL1 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Rattus norvegicus)
        
        SCF E3 ubiquitin ligase [cytosol] (Rattus norvegicus)
        
        F-box protein [cytosol] (Rattus norvegicus)
        
        Fbxo44 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D4A6R1

Gene Names

Fbxo44

Reference Genes

ENSEMBL:ENSRNOG00000009298

ENSEMBL:ENSRNOG00000009298.9 Fbxo44

Other Identifiers

10881590

1380379_at

17812605

500587

5661948

5819629

6078752

6273335

6273668

6362661

6452946

6453393

6504983

GE1121455

GO:0005515

GO:0010498

GO:0019005

GO:0030163

ILMN_1352377

PH_rn_0001478

Participates

as a candidate of

E3 ligases in proteasomal degradation [cytosol] (Rattus norvegicus)

as a member of

F-box protein [cytosol] (Rattus norvegicus)

Inferred From

FBXO44 [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSRNOG00000009298, ENSRNOP00000059513, ENSRNOT00000067059

RGD

1562463

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