Reactome | RPS19 [cytosol]

RPS19 [cytosol]

Stable Identifier

R-RNO-72343

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

cytosol

Synonyms

D3ZGN8

Locations in the PathwayBrowser

Expand all

Metabolism of RNA (Rattus norvegicus)

- Nonsense-Mediated Decay (NMD) (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Rattus norvegicus)
    - SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPS19 [cytosol] (Rattus norvegicus)
        
        RPS19 [cytosol] (Rattus norvegicus)
      - SMG1:UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPS19 [cytosol] (Rattus norvegicus)
        
        RPS19 [cytosol] (Rattus norvegicus)
    - SMG6 hydrolyzes mRNA with premature termination codon (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPS19 [cytosol] (Rattus norvegicus)
        
        RPS19 [cytosol] (Rattus norvegicus)
    - p-4S-UPF1 recruits SMG5, SMG7, SMG6, PNRC2, DCP1A, and PP2A (Rattus norvegicus)
      - Phosphorylated UPF1:SMG5:SMG7:SMG6:PP2A:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPS19 [cytosol] (Rattus norvegicus)
        
        RPS19 [cytosol] (Rattus norvegicus)
      - SMG1:Phosphorylated UPF1:EJC:Translated mRNP [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPS19 [cytosol] (Rattus norvegicus)
        
        RPS19 [cytosol] (Rattus norvegicus)
  - Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) (Rattus norvegicus)
    - Formation of UPF1:eRF3 complex on mRNA with a premature termination codon and no Exon Junction Complex (Rattus norvegicus)
      - Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPS19 [cytosol] (Rattus norvegicus)
        
        RPS19 [cytosol] (Rattus norvegicus)
      - UPF1:eRF3 Complex on Translated mRNA [cytosol] (Rattus norvegicus)
        
        Translated mRNA Complex with Premature Termination Codon Not Preceding Exon Junction [cytosol] (Rattus norvegicus)
        
        80S ribosome [cytosol] (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPS19 [cytosol] (Rattus norvegicus)
        
        RPS19 [cytosol] (Rattus norvegicus)
- rRNA processing (Rattus norvegicus)
  - rRNA processing in the nucleus and cytosol (Rattus norvegicus)
    - Major pathway of rRNA processing in the nucleolus and cytosol (Rattus norvegicus)
      - 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol (Rattus norvegicus)
        
        40S ribosomal complex [cytosol] (Rattus norvegicus)
        
        Homologues of RPS19 [cytosol] (Rattus norvegicus)
        
        RPS19 [cytosol] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZGN8

Reference Genes

ENSEMBL:ENSRNOG00000033146

Other Identifiers

103690015

10704411

10705058

10740379

10778918

10783353

10795546

10892937

1371377_at

17613551

17614309

5693088

5879551

5884403

6121661

6200096

6236065

6429437

9313957

AABR07002611

ENSRNOG00000033146

ENSRNOP00000043543

ENSRNOT00000049028

EntrezGene:103690015

EntrezGene:LOC103690015

GE22118

GO:0000028

GO:0003674

GO:0003735

GO:0005198

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005829

GO:0005840

GO:0006412

GO:0008150

GO:0009058

GO:0022607

GO:0022618

GO:0022627

GO:0032991

GO:0034641

GO:0042254

GO:0043226

GO:0065003

ILMN_1351142

IPR001266

IPR018277

IPR036390

IPR038111

LOC103690015

LOC103690015-201

PF01090

SM01413

UPI00062E123B

X51707cds_s_at

XM_002728672

XP_002728718

Participant Of

hasMember

Homologues of RPS19 [cytosol]

Other forms of this molecule

RPS19 [nucleoplasm]

Inferred From

RPS19 [cytosol] (Homo sapiens)