Reactome | phospho-Rad52 [nucleoplasm]

phospho-Rad52 [nucleoplasm]

Stable Identifier

R-RNO-5686588

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

nucleoplasm

Synonyms

p-Y104-RAD52, D3ZZL1

Locations in the PathwayBrowser

Expand all

DNA Repair (Rattus norvegicus)

- DNA Double-Strand Break Repair (Rattus norvegicus)
  - Homology Directed Repair (Rattus norvegicus)
    - HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Rattus norvegicus)
      - HDR through Single Strand Annealing (SSA) (Rattus norvegicus)
        
        ABL1 phosphorylates RAD52 (Rattus norvegicus)
        
        p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)
        
        phospho-Rad52 [nucleoplasm] (Rattus norvegicus)
        
        Association of RAD51 with RAD52:DNA double-strand break ends (Rattus norvegicus)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)
        
        phospho-Rad52 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)
        
        phospho-Rad52 [nucleoplasm] (Rattus norvegicus)
        
        Association of RAD52 with the RPA complex at resected DNA DSBs (Rattus norvegicus)
        
        p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)
        
        phospho-Rad52 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)
        
        phospho-Rad52 [nucleoplasm] (Rattus norvegicus)
        
        ERCC1:XPF cleaves flaps generated by SSA (Rattus norvegicus)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)
        
        phospho-Rad52 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)
        
        phospho-Rad52 [nucleoplasm] (Rattus norvegicus)
        
        RAD52 promotes single strand annealing at resected DNA DSBs (Rattus norvegicus)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)
        
        phospho-Rad52 [nucleoplasm] (Rattus norvegicus)
        
        RAD51:p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52:p-RPA:ATR:ATRIP:DNA DSBs with annealed 3' ssDNA overhangs and displaced flaps:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)
        
        phospho-Rad52 [nucleoplasm] (Rattus norvegicus)
        
        p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)
        
        phospho-Rad52 [nucleoplasm] (Rattus norvegicus)

External Reference Information

External Reference

UniProt:D3ZZL1

Gene Names

Rad52

Reference Genes

BioGPS Gene:297561 Rad52

ENSEMBL:ENSRNOG00000009742

ENSEMBL:ENSRNOG00000009742.9 Rad52

Monarch:297561 Rad52

NCBI Gene:297561 Rad52

UCSC:D3ZZL1 Rad52

Reference Transcript

Other Identifiers

10858260

1377902_a_at

1397430_at

17786559

297561

5628163

5664095

5799300

5866010

5917818

6017350

6060487

6189028

6207714

6210308

6409939

6428133

6604018

6622440

6723254

A_44_P400922

GE1194667

GE1199504

GO:0000724

GO:0000730

GO:0003677

GO:0003697

GO:0005634

GO:0006281

GO:0006310

GO:0010792

GO:0032991

GO:0032993

GO:0034599

GO:0042802

GO:0043226

GO:0045002

GO:0065003

GO:2000819

ILMN_1368944

PH_rn_0008319

rc_AA893822_at

Participates

as a component of

p-Y104-RAD52 heptamer [nucleoplasm] (Rattus norvegicus)

Other forms of this molecule

Rad52 [nucleoplasm]

Inferred From

p-Y104-RAD52 [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 104 (in Homo sapiens)

Coordinate

104

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

XP_008761455.1, XP_008761454.1

Ensembl

ENSRNOP00000013070, ENSRNOT00000013070, ENSRNOG00000009742

RGD

1304975

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