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phospho-p-T774-PKN1 [nucleoplasm]
Stable Identifier
R-RNO-5625721
Type
Protein [EntityWithAccessionedSequence]
Species
Rattus norvegicus
Compartment
nucleoplasm
Synonyms
Q63433
Locations in the PathwayBrowser
Expand all
Signal Transduction (Rattus norvegicus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases activate PKNs (Rattus norvegicus)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Rattus norvegicus)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
Demethylase KDM4C binds KLK2 and KLK3 promoters (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
PKN1 stimulates association of AR with NCOA2 (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:NCOA2 [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen complex translocates to the nucleus (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
phospho-p-T774-PKN1 [nucleoplasm] (Rattus norvegicus)
External Reference Information
External Reference
UniProt:Q63433
Reference Genes
BioGPS Gene:29355
ENSEMBL:ENSRNOG00000004131
ENSEMBL:ENSRNOG00000004131.7
ENSEMBL:ENSRNOG00055007359
ENSEMBL:ENSRNOG00060013266
ENSEMBL:ENSRNOG00065009743
KEGG Gene (Rattus norvegicus):29355
Monarch:29355
NCBI Gene:29355
Reference Transcript
RefSeq:NM_017175.2
Other Identifiers
10806829
1386992_at
17728903
29355
5647087
5651833
5801900
5837304
5864332
5876926
5965165
6074143
6090298
6136280
6170685
6198733
6258408
6279737
6318296
6359832
6488437
6518619
6519539
6554221
6588227
6593073
6597581
6664783
A_44_P144277
D26180_at
GE20395
GE21585
GO:0003824
GO:0004672
GO:0004674
GO:0005524
GO:0006468
GO:0007165
GO:0016740
GO:0023052
GO:0031267
GO:0036211
GO:0140096
Participates
as a component of
p-T774-PKN1:AR:Androgen:NCOA2 [nucleoplasm] (Rattus norvegicus)
p-T774-PKN1:AR:Androgen [nucleoplasm] (Rattus norvegicus)
Other forms of this molecule
PKN1 [cytosol]
phospho-p-T774-PKN1 [cytosol]
Inferred From
p-T774-PKN1 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 774 (in Homo sapiens)
Coordinate
774
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
RefSeq
NP_058871.2
Ensembl
ENSRNOT00000005770
,
ENSRNOG00000004131
,
ENSRNOP00000005770
PRO
Q63433
RGD
69308
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