Reactome | phospho-p-Y1252,Y1336,Y1474-GRIN2B [plasma membrane]

phospho-p-Y1252,Y1336,Y1474-GRIN2B [plasma membrane]

Stable Identifier

R-RNO-3928477

Type

Protein [EntityWithAccessionedSequence]

Species

Rattus norvegicus

Compartment

plasma membrane

Synonyms

Q00960

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q00960 Grin2b

Gene Names

Grin2b

Chain

signal peptide:1-26, chain:27-1482

Reference Genes

BioGPS Gene:24410 Grin2b

KEGG Gene (Rattus norvegicus):24410 Grin2b

Monarch:24410 Grin2b

NCBI Gene:24410 Grin2b

UCSC:Q00960 Grin2b

Reference Transcript

RefSeq:NM_012574.1 Grin2b

Participates

as a component of

Glu:p-NMDAR:Gly [plasma membrane] (Rattus norvegicus)

Other forms of this molecule

p-Y1472-Grin2b [plasma membrane]

Grin2b [endoplasmic reticulum membrane]

GRIN2B [endoplasmic reticulum membrane]

p-Y-Grin2b [plasma membrane]

Grin2b [plasma membrane]

GRIN2B [plasma membrane]

Inferred From

p-Y1252,Y1336,Y1474-GRIN2B [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 1252 (in Homo sapiens)

Coordinate

1252

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 1336 (in Homo sapiens)

Coordinate

1336

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 1474 (in Homo sapiens)

Coordinate

1474

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_036706.1

ZINC - Investigational

NMDE2_RAT

ZINC - World Drugs

NMDE2_RAT

ZINC - Substances

NMDE2_RAT

ZINC - Biogenic

NMDE2_RAT

ZINC target

Q00960

PRO

Q00960

ZINC - Predictions - Purchasable

NMDE2_RAT

RGD

2738

PDB

5FXI, 5TPZ, 7TET, 6WHW, 7TEB, 6WHV, 3JPY, 5FXH, 6CNA, 6E7X, 5FXK, 8G18, 6E7S, 7TEE, 6WHX, 5FXJ, 6E7R, 6WHR, 7SAB, 3QEL, 7TEQ, 6WI1, 6E7U, 6WI0, 6WHY, 7SAA, 6E7T, 6WHU, 7TES, 3JPW, 6WHT, 7SAD, 4PE5, 6E7W, 7SAC, 7TE9, 7TER, 6WHS, 7TE6, 3QEM, 5B3J, 5FXG, 6E7V

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P31016 Dlg4	3	Dlg4 [cytosol] (R-RNO-6794248) Dlg4 [endocytic vesicle membrane] (R-RNO-416847) Dlg4 [plasma membrane] (R-RNO-9612601)	0.915	11
UniProt:P35439 Grin1	2	Grin1 [endoplasmic reticulum membrane] (R-RNO-9609841) Grin1 [plasma membrane] (R-RNO-9610826)	0.866	13
UniProt:A0A1L8F5J9-8 GRIN1			0.74	6
UniProt:Q62936	2	Dlg3 [cytosol] (R-RNO-6794232) Dlg3 [plasma membrane] (R-RNO-443609)	0.704	6
UniProt:P11798 Camk2a	6	phospho-p-T286-CAMK2A [plasma membrane] (R-MMU-432796) p-T286-Camk2a [nucleoplasm] (R-MMU-9608160) phospho-p-T286-CAMK2A [endocytic vesicle membrane] (R-MMU-416999) phospho-p-T286,T305,T306-CAMK2A [cytosol] (R-MMU-4332334) CAMK2A [cytosol] (R-MMU-4332329) phospho-p-T286-CAMK2A [cytosol] (R-MMU-445368)	0.704	4
UniProt:P11275 Camk2a	6	phospho-p-T286-CAMK2A [plasma membrane] (R-RNO-432796) phospho-p-T286-CAMK2A [nucleoplasm] (R-RNO-444797) phospho-p-T286-CAMK2A [endocytic vesicle membrane] (R-RNO-416999) phospho-p-T286,T305,T306-CAMK2A [cytosol] (R-RNO-4332334) Camk2a [cytosol] (R-RNO-9611390) p-T286-Camk2a [cytosol] (R-RNO-9618632)	0.589	2
UniProt:Q9Z252 Lin7b	1	Lin7b [plasma membrane] (R-RNO-6794272)	0.576	5
UniProt:Q63ZW7 INADL			0.508	4