Active Plcg1 hydrolyses PIP2

Stable Identifier
R-RNO-182061
Type
Reaction [transition]
Species
Rattus norvegicus
Compartment
General
SVG |   | PPTX  | SBGN
Active Plcg1 hydrolyses PIP2

Inositol 1,4,5-triphosphate (IP3) is a second messenger produced by phospholipase C (PLC) metabolism of phosphoinositol 4,5-bisphosphate (PIP2) (Canossa et al. 2001).

Literature References
PubMed ID Title Journal Year
11285228 Regulated secretion of neurotrophins by metabotropic glutamate group I (mGluRI) and Trk receptor activation is mediated via phospholipase C signalling pathways

Canossa, M, Gartner, A, Campana, G, Inagaki, N, Thoenen, H

EMBO J 2001
Participants
Catalyst Activity
Catalyst Activity
Title
phosphatidylinositol phospholipase C activity of p-Plcg1 [plasma membrane]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created