EP300 acetylates Foxo4

Stable Identifier
R-NUL-9617757
Type
Reaction [transition]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
EP300 acetylates Foxo4
Recombinant human EP300 histone acetyltransferase acetylates recombinant mouse Foxo4 (Dansen et al. 2009).
Literature References
PubMed ID Title Journal Year
19648934 Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity

van Leenen, D, Burgering, BM, Yodoi, J, van Triest, MH, Holstege, FC, Meppelink, A, de Keizer, PL, Szypowska, A, Koerkamp, MG, Smits, LM, Brenkman, AB, Dansen, TB

Nat. Chem. Biol. 2009
Participants
Input
Output
Catalyst Activity

peptide-lysine-N-acetyltransferase activity of EP300-S-S-Foxo4:Foxo4-S-S-EP300 [nucleoplasm]

Physical Entity
EP300-S-S-Foxo4:Foxo4-S-S-EP300 [nucleoplasm] (Homo sapiens)
Activity
peptide-lysine-N-acetyltransferase activity (GO:0061733)
Orthologous Events
EP300,CREBBP acetylate FOXO4 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-10-11)
Reviewed
Bertaggia, E  (2018-10-26)
Donlon, T  (2018-10-17)
Created
Orlic-Milacic, M  (2018-08-30)
Cite Us!