FLT4 gene expression is stimulated by Notch4

Stable Identifier
R-NUL-9604519
Type
Reaction [omitted]
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
FLT4 gene expression is stimulated by Notch4

Recombinant mouse Notch4 intracellular domain fragment (NICD4) stimulates transcription from the promoter of the human FLT4 (VEGFR) gene (Shawber et al. 2007).

Literature References
PubMed ID Title Journal Year
17948123 Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression

Shawber, CJ, Funahashi, Y, Francisco, E, Vorontchikhina, M, Kitamura, Y, Stowell, SA, Borisenko, V, Feirt, N, Podgrabinska, S, Shiraishi, K, Chawengsaksophak, K, Rossant, J, Accili, D, Skobe, M, Kitajewski, J

J. Clin. Invest. 2007
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This event is regulated
Orthologous Events
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