Notch4 binds FLT4 gene promoter

Stable Identifier
R-NUL-9604511
Type
Reaction [binding]
Species
Mus musculus
Compartment
ReviewStatus
5/5
General
SVG |   | PPTX  | SBGN
Notch4 binds FLT4 gene promoter
Recombinant mouse Notch4 intracellular domain fragment (NICD4), in complex with human RBPJ (CSL) and MAML, binds to RBPJ (CSL) response elements in the promoter of the human FLT4 (VEGFR) gene (Shawber et al. 2007).
Literature References
PubMed ID Title Journal Year
17948123 Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression

Feirt, N, Vorontchikhina, M, Chawengsaksophak, K, Borisenko, V, Stowell, SA, Shiraishi, K, Shawber, CJ, Skobe, M, Kitajewski, J, Podgrabinska, S, Francisco, E, Kitamura, Y, Rossant, J, Accili, D, Funahashi, Y

J. Clin. Invest. 2007
Participants
Orthologous Events
Authored
Reviewed
Created
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