Ntrk2 binds Tiam1

Stable Identifier
R-NUL-9033304
Type
Reaction [binding]
Species
Mus musculus
Compartment
plasma membrane, cytosol
ReviewStatus
5/5
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Ntrk2 binds Tiam1
Mouse Ntrk2 (TrkB), stimulated by recombinant human BDNF, and phosphorylated by Cdk5 at serine residue S478, binds to mouse Tiam1, a Rac1 guanine nucleotide exchange factor (GEF) (Lai et al. 2012).
Literature References
PubMed ID Title Journal Year
23064382 TrkB phosphorylation by Cdk5 is required for activity-dependent structural plasticity and spatial memory

Palko, ME, Xu, P, Ip, NY, Cheung, MC, Lok, KC, Cheung, ZH, Xie, H, Tessarollo, L, Lai, KO, Yung, WH, Liang, Z, Wong, AS

Nat. Neurosci. 2012
Participants
Input
Output
Orthologous Events
NTRK2 binds TIAM1 (Homo sapiens)
Authored
Orlic-Milacic, M  (2018-01-05)
Reviewed
Castrén, E  (2018-02-13)
Antila, H  (2018-02-13)
Created
Orlic-Milacic, M  (2017-12-20)
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