Doublecortin binds phosphorylated neurofascin

Stable Identifier
R-NUL-443772
Type
Reaction [binding]
Species
Homo sapiens
Compartment
General
SVG |   | PPTX  | SBGN
Doublecortin binds phosphorylated neurofascin

Doublecortin is a microtubule associated protein expressed in neurons. Mutated doublecortin has been linked to the neuronal migration disorder X linked subcortical laminar heterotopia (double cortex)/lissencephaly. It binds neurofascin when the FIGQY motif of the latter protein is phosphorylated.

Literature References
PubMed ID Title Journal Year
12223548 A new activity of doublecortin in recognition of the phospho-FIGQY tyrosine in the cytoplasmic domain of neurofascin

Kizhatil, K, Wu, YX, Sen, A, Bennett, V

J Neurosci 2002
Participants
Orthologous Events
Authored
Reviewed
Created