IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2

Stable Identifier
R-MMU-8987202
Type
Reaction [omitted]
Species
Mus musculus
Compartment
Synonyms
JAK1 and TYK2 are phosphorylated by IFNL1:IFNLR1:JAK1:IL10RB:TYK2 receptor complex, JAK1 and tyk2 are phosphorylated after il29-il29 receptor interaction
Locations in the PathwayBrowser
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This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Participants
Participant Of
Catalyst Activity
Catalyst Activity
Title
transmembrane receptor protein tyrosine kinase activity of IFNL1:IFNLR1:JAK1:IL10RB:TYK2 [plasma membrane]
Physical Entity
Activity
Inferred From
Created