Reactome | Tulp4 [cytosol]

Tulp4 [cytosol]

Stable Identifier

R-MMU-8863142

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

cytosol

Synonyms

TULP4, Q9JIL5

Locations in the PathwayBrowser

Expand all

Metabolism of proteins (Mus musculus)

- Post-translational protein modification (Mus musculus)
  - Neddylation (Mus musculus)
    - AcM-UBE2F transfers NEDD8 to CRL5 E3 ubiquitin ligase complex (Mus musculus)
      - NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Mus musculus)
        
        CUL5-box protein [cytosol] (Mus musculus)
        
        Tulp4 [cytosol] (Mus musculus)
      - NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Mus musculus)
        
        CUL5-box protein [cytosol] (Mus musculus)
        
        Tulp4 [cytosol] (Mus musculus)
    - CAND1 binds cytosolic CRL E3 ubiquitin ligases (Mus musculus)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Mus musculus)
        
        CRL E3 ubiquitin ligases [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Mus musculus)
        
        CUL5-box protein [cytosol] (Mus musculus)
        
        Tulp4 [cytosol] (Mus musculus)
      - CRL E3 ubiquitin ligases [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Mus musculus)
        
        CUL5-box protein [cytosol] (Mus musculus)
        
        Tulp4 [cytosol] (Mus musculus)
    - COMMDs displace CAND1 from cytosolic CRL E3 ubiquitin ligase complexes (Mus musculus)
      - CRL E3 ubiquitin ligase:CAND1 [cytosol] (Mus musculus)
        
        CRL E3 ubiquitin ligases [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Mus musculus)
        
        CUL5-box protein [cytosol] (Mus musculus)
        
        Tulp4 [cytosol] (Mus musculus)
      - CRL E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Mus musculus)
        
        CUL5-box protein [cytosol] (Mus musculus)
        
        Tulp4 [cytosol] (Mus musculus)
    - COP9 signalosome deneddylates cytosolic CRL E3 ubiquitin ligase complexes (Mus musculus)
      - CRL E3 ubiquitin ligase complex:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Mus musculus)
        
        CUL5-box protein [cytosol] (Mus musculus)
        
        Tulp4 [cytosol] (Mus musculus)
      - NEDD8 CRL E3 ubiquitin ligases:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
        
        NEDD8-CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
        
        NEDD8-CRL5 E3 ligase [cytosol] (Mus musculus)
        
        CUL5-box protein [cytosol] (Mus musculus)
        
        Tulp4 [cytosol] (Mus musculus)
    - NEDD8:AcM-UBE2F binds CRL5 E3 ubiquitin ligase complex (Mus musculus)
      - CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Mus musculus)
        
        CUL5-box protein [cytosol] (Mus musculus)
        
        Tulp4 [cytosol] (Mus musculus)
      - NEDD8-AcM-UBE2F:CRL5 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1Ds [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase:COMMDs:CCDC22 [cytosol] (Mus musculus)
        
        CRL5 E3 ubiquitin ligase [cytosol] (Mus musculus)
        
        CUL5-box protein [cytosol] (Mus musculus)
        
        Tulp4 [cytosol] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9JIL5

Gene Names

Tulp4

Reference Genes

BioGPS Gene:68842 Tulp4

ENSEMBL:ENSMUSG00000034377

ENSEMBL:ENSMUSG00000034377.11 Tulp4

KEGG Gene (Mus musculus):68842 Tulp4

Monarch:68842 Tulp4

NCBI Gene:68842 Tulp4

UCSC:Q9JIL5 Tulp4

Reference Transcript

Other Identifiers

10441497

1440282_at

1448548_at

160775_at

17332860

4326679

4390437

4440916

4481428

4512583

4594453

4634545

4675892

4763510

4804149

4811550

4871050

4901112

4927253

4935872

4967916

4992638

5007928

5064041

5319943

5328452

5329207

5346177

5378600

5473302

5531953

5541969

5543525

68842

A_30_P01019877

A_30_P01022735

A_30_P01031647

A_51_P248999

A_52_P600048

A_55_P1986833

A_55_P2730333

A_66_P122094

GE42111

GO:0005515

GO:0005737

GO:0016567

GO:0036211

ILMN_1252283

aa673986_s_at

mMC025314

Participates

as a member of

CUL5-box protein [cytosol] (Mus musculus)

Inferred From

TULP4 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_473381.1, XP_006523314.1

Ensembl

ENSMUSG00000034377, ENSMUSP00000049248, ENSMUST00000039655

PRO

Q9JIL5

MGI

1916092