Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Contributors
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
PolyUb-MAP3K7 [cytosol]
Stable Identifier
R-MMU-6782968
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q62073
Locations in the PathwayBrowser
Expand all
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Deubiquitination (Mus musculus)
Ub-specific processing proteases (Mus musculus)
USP18 deubiquitinates TAK1:TAB1 (Mus musculus)
USP18:PolyUb-MAP3K7:TAB1 [cytosol] (Mus musculus)
PolyUb-MAP3K7:TAB1 [cytosol] (Mus musculus)
PolyUb-MAP3K7 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q62073 Map3k7
Gene Names
Map3k7, Tak1
Chain
chain:1-579
Reference Genes
BioGPS Gene:26409 Map3k7
ENSEMBL:ENSMUSG00000028284.14 Map3k7
KEGG Gene (Mus musculus):26409 Map3k7
Monarch:26409 Map3k7
NCBI Gene:26409 Map3k7
UCSC:Q62073 Map3k7
Reference Transcript
RefSeq:NM_172688.3 Map3k7
Other Identifiers
10503680
108785_at
136564_at
1419988_at
1425795_a_at
1426627_at
1455441_at
160854_at
17412350
26409
4523055
4544367
4636504
4785039
4788587
4818230
4846645
4857331
4995133
5004132
5121058
5178154
5215209
5226625
5235667
5263133
5291479
5324583
5432353
5503586
5522793
5550079
5575846
5594822
5604117
A_52_P175952
A_55_P2049086
A_55_P2127804
A_55_P2640840
D76446_s_at
GO:0000165
GO:0000166
GO:0000287
GO:0001223
GO:0001525
GO:0001649
GO:0001841
GO:0002376
GO:0002726
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0004708
GO:0004709
GO:0005114
GO:0005515
GO:0005524
GO:0005694
GO:0005737
GO:0005829
GO:0005886
GO:0006325
GO:0006338
GO:0006468
GO:0006914
GO:0006915
GO:0006954
GO:0006955
GO:0007165
GO:0007179
GO:0007249
GO:0007252
GO:0007254
GO:0008349
GO:0008385
GO:0010508
GO:0010629
GO:0012501
GO:0014069
GO:0016020
GO:0016239
GO:0016301
GO:0016310
GO:0016740
GO:0018107
GO:0023052
GO:0030154
GO:0030971
GO:0031625
GO:0032743
GO:0034142
GO:0035173
GO:0035556
GO:0036211
GO:0038066
GO:0038172
GO:0038173
GO:0042742
GO:0042802
GO:0043123
GO:0043226
GO:0043276
GO:0043410
GO:0043507
GO:0045787
GO:0045793
GO:0046330
GO:0046872
GO:0048856
GO:0048870
GO:0051403
GO:0060348
GO:0060546
GO:0065003
GO:0071356
GO:0071560
GO:0097110
GO:0097190
GO:0098542
GO:0106310
GO:0120283
GO:0140096
GO:0140297
GO:0140672
GO:1902443
GO:1904385
GO:1904707
GO:1904754
GO:1990450
GO:2000377
GO:2000378
GO:2001234
ILMN_2707188
mMC002557
Participates
as a component of
PolyUb-MAP3K7:TAB1 [cytosol] (Mus musculus)
Other forms of this molecule
Phospho TAK1 [cytosol]
phospho-p-T187-MAP3K7 [cytosol]
K63polyUb-34,158-TAK1 [cytosol]
phospho-K63polyUb-34,158-p-T178,184,187,S192-TAK1 [cytosol]
phospho-p-MAP3K7 [cytosol]
MAP3K7 [endosome membrane]
phospho-p-T184,T187-MAP3K7 [endosome membrane]
MAP3K7 [cytosol]
phospho-p-T184,T187-MAP3K7 [cytosol]
Inferred From
PolyUb-MAP3K7 [cytosol]
(Homo sapiens)
Modified Residues
Name
ubiquitinylated lysine (PolyUb [cytosol]) at unknown position
Modification
PolyUb [cytosol]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_766276.1
Ensembl
ENSMUST00000080933
,
ENSMUSP00000079734
,
ENSMUSG00000028284
PRO
Q62073
MGI
1346877
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q99K90 Tab2
7
Phospho TAB2 [cytosol]
(R-MMU-205966)
Tab2 [nucleoplasm]
(R-MMU-1253317)
Tab2 [cytosol]
(R-MMU-205843)
Tab2 [nucleoplasm]
(R-MMU-1253323)
Tab2 [plasma membrane]
(R-MMU-168116)
Tab2 [endosome membrane]
(R-MMU-450279)
Tab2 [cytosol]
(R-MMU-168117)
0.757
8
UniProt:P70340 Smad1
4
Ub-SMAD1 [cytosol]
(R-MMU-6782768)
SMAD1 [cytosol]
(R-MMU-201468)
phospho-p-S463,S465-SMAD1 [cytosol]
(R-MMU-201464)
p-S463,S465-Smad1 [nucleoplasm]
(R-MMU-9748885)
0.602
3
UniProt:Q9NYJ8 TAB2
4
TAB2 [cytosol]
(R-HSA-168117)
TAB2 [endosome membrane]
(R-HSA-450279)
TAB2 [plasma membrane]
(R-HSA-168116)
TAB2 [nucleoplasm]
(R-HSA-1253323)
0.59
2
UniProt:Q86Y07-1 VRK2
0.576
3
UniProt:Q8CF89 Tab1
3
Phospho TAB1 [cytosol]
(R-MMU-206141)
Tab1 [endosome membrane]
(R-MMU-450238)
Tab1 [cytosol]
(R-MMU-167923)
0.564
2
UniProt:Q9WVI9-2 MAPK8IP1
0.499
4
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text