Phosphorylation of FADK1

Stable Identifier
R-MMU-421694
Type
Reaction [transition]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Phosphorylation of FADK1

FADK1 interacts with the C-terminal P3 domain of DCC complexed with Netrin-1, and undergoes tyrosine phosphorylation and activation. Netrin-1-DCC binding thus leads to the autophosphorylation of tyrosine 393 in FADK1.

Literature References
PubMed ID Title Journal Year
15494733 Focal adhesion kinase in netrin-1 signaling

Ren, XR, Ming, GL, Xie, Y, Hong, Y, Sun, DM, Zhao, ZQ, Feng, Z, Wang, Q, Shim, S, Chen, ZF, Song, HJ, Mei, L, Xiong, WC

Nat Neurosci 2004
Participants
Catalyst Activity
Catalyst Activity
Title
protein tyrosine kinase activity of Focal adhesion kinase 1 [cytosol]
Physical Entity
Activity
Orthologous Events
Authored
Reviewed
Created