Reactome | PHC2 [nucleoplasm]

PHC2 [nucleoplasm]

Stable Identifier

R-MMU-389112

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

nucleoplasm

Synonyms

Q9QWH1

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Mus musculus)

- RNA Polymerase II Transcription (Mus musculus)
  - Generic Transcription Pathway (Mus musculus)
    - Transcriptional regulation by RUNX1 (Mus musculus)
      - RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known (Mus musculus)
        
        RUNX1 binds PRC1 complexes (Mus musculus)
        
        (PRC1.4,PRC1.5) [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        PHC1,PHC2,PHC3 [nucleoplasm] (Mus musculus)
        
        PHC2 [nucleoplasm] (Mus musculus)
        
        RUNX1:CBFB:(PRC1.4,PRC1.5) [nucleoplasm] (Mus musculus)
        
        (PRC1.4,PRC1.5) [nucleoplasm] (Mus musculus)
        
        PRC1.4 [nucleoplasm] (Mus musculus)
        
        PHC1,PHC2,PHC3 [nucleoplasm] (Mus musculus)
        
        PHC2 [nucleoplasm] (Mus musculus)

External Reference Information

External Reference

UniProt:Q9QWH1

Reference Genes

BioGPS Gene:54383

ENSEMBL:ENSMUSG00000028796

ENSEMBL:ENSMUSG00000028796.18

KEGG Gene (Mus musculus):54383

Monarch:54383

NCBI Gene:54383

UCSC:Q9QWH1

Reference Transcript

Other Identifiers

10508351

1416048_at

1437239_x_at

17418857

4312258

4438256

4446619

4479793

4585423

4659813

4770978

4779946

4814020

4870122

4928755

4952803

5051550

5080331

5102427

5142497

5143348

5223178

5240794

5267819

5338328

5434197

54383

5535602

5543603

5553949

92867_at

AA415044_rc_f_at

A_51_P457388

A_55_P2027067

GE37267

GO:0000792

GO:0003677

GO:0003682

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006351

GO:0006355

GO:0007283

GO:0008270

GO:0022414

GO:0031519

GO:0032991

GO:0035102

GO:0042393

GO:0042802

GO:0043226

GO:0045892

GO:0046872

ILMN_1226754

ILMN_2767625

aa682040_rc_f_at

mMC017440

Participates

as a component of

as a member of

PHC1,PHC2,PHC3 [nucleoplasm] (Mus musculus)

Inferred From

PHC2 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_001182012.1, XP_006503301.1, NP_001182059.1, XP_017175809.1, NP_061244.1, XP_006503300.1

Ensembl

ENSMUSP00000030588, ENSMUST00000106079, ENSMUST00000030588, ENSMUSP00000101689, ENSMUST00000106080, ENSMUSP00000101690, ENSMUSG00000028796

PRO

Q9QWH1

MGI

1860454

PDB

2NA1

Interactors (2)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P23798 Pcgf2	2	Pcgf2 [nucleoplasm] (R-MMU-5619463) Pcgf2 [nucleoplasm] (R-MMU-389115)	0.756	5
UniProt:P49138	5	MAPKAPK2 [cytosol] (R-MMU-187743) phospho-p-T222,S272-MAPKAPK2 [nucleoplasm] (R-MMU-199936) phospho-p-S272,T222,T334-MAPKAPK2 [cytosol] (R-MMU-187760) phospho-p-T222,S272,T334-MAPKAPK2 [nucleoplasm] (R-MMU-450268) MAPKAPK2 [nucleoplasm] (R-MMU-450235)	0.611	5