Reactome | Sstr1 [plasma membrane]

Sstr1 [plasma membrane]

Stable Identifier

R-MMU-374741

Type

Protein [EntityWithAccessionedSequence]

Species

Mus musculus

Compartment

plasma membrane

Synonyms

SSTR1, P30873

Locations in the PathwayBrowser

Expand all

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR downstream signalling (Mus musculus)
    - G alpha (i) signalling events (Mus musculus)
      - Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin receptors [plasma membrane] (Mus musculus)
        
        Sstr1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin receptors [plasma membrane] (Mus musculus)
        
        Sstr1 [plasma membrane] (Mus musculus)
      - Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin receptors [plasma membrane] (Mus musculus)
        
        Sstr1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin receptors [plasma membrane] (Mus musculus)
        
        Sstr1 [plasma membrane] (Mus musculus)
      - The Ligand:GPCR:Gi complex dissociates (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin receptors [plasma membrane] (Mus musculus)
        
        Sstr1 [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
        
        Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin receptors [plasma membrane] (Mus musculus)
        
        Sstr1 [plasma membrane] (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Somatostatin receptors bind somatostatin and cortistatin (Mus musculus)
        
        Somatostatin receptor:somatostatin [plasma membrane] (Mus musculus)
        
        Somatostatin receptors [plasma membrane] (Mus musculus)
        
        Sstr1 [plasma membrane] (Mus musculus)
        
        Somatostatin receptors [plasma membrane] (Mus musculus)
        
        Sstr1 [plasma membrane] (Mus musculus)

External Reference Information

External Reference

UniProt:P30873

Gene Names

Sstr1

Reference Genes

BioGPS Gene:20605 Sstr1

ENSEMBL:ENSMUSG00000035431

ENSEMBL:ENSMUSG00000035431.5 Sstr1

KEGG Gene (Mus musculus):20605 Sstr1

Monarch:20605 Sstr1

NCBI Gene:20605 Sstr1

UCSC:P30873 Sstr1

Reference Transcript

Other Identifiers

101318_at

10395889

1450527_at

17275678

20605

4597039

4729154

4931768

4980891

5003171

5258021

5384689

A_51_P432950

GE118368

GO:0004930

GO:0004994

GO:0005515

GO:0005886

GO:0007165

GO:0007186

GO:0007215

GO:0007218

GO:0007283

GO:0016020

GO:0021549

GO:0022414

GO:0023052

GO:0030900

GO:0038170

GO:0042594

GO:0042923

GO:0043005

GO:0048856

GO:0060089

GO:0071392

GO:1990830

ILMN_2728465

Msa.1384.0_at

mMC017162

Participates

as a member of

Somatostatin receptors [plasma membrane] (Mus musculus)

Inferred From

SSTR1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_033242.1, XP_006515697.1

ZINC target

P30873

Ensembl

ENSMUST00000110671, ENSMUSP00000106299, ENSMUSG00000035431

PRO

P30873

ZINC - Predictions - Purchasable

SSR1_MOUSE

MGI

98327

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q62108 Dlg4	3	SAP-90 [plasma membrane] (R-MMU-443606) Dlg4 [endocytic vesicle membrane] (R-MMU-416847) Dlg4 [cytosol] (R-MMU-6794267)	0.544	3