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Anapc5 [cytosol]
Stable Identifier
R-MMU-174211
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
ANAPC5, Q8BTZ4
Locations in the PathwayBrowser
Expand all
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
Mitotic Spindle Checkpoint (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Separation of Sister Chromatids (Mus musculus)
Association of Securin with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Regulation of mitotic cell cycle (Mus musculus)
APC/C-mediated degradation of cell cycle proteins (Mus musculus)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Mus musculus)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Degradation of multiubiquitinated cell cycle proteins (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Mus musculus)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of mitotic proteins (Mus musculus)
APC/C:Cdc20 mediated degradation of Cyclin B (Mus musculus)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Degradation of multiubiquitinated Cyclin B (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Mus musculus)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
APC/C:Cdc20 mediated degradation of Securin (Mus musculus)
Association of Securin with Cdc20:APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Degradation of multiubiquitinated Securin (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Mus musculus)
CDC20:p-APC/C:PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Mus musculus)
APC-Cdc20 mediated degradation of Nek2A (Mus musculus)
Association of Nek2A with MCC:APC/C (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Degradation of multiubiquitinated Nek2A (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Multiubiquitination of Nek2A (Mus musculus)
Multiubiquitinated Nek2A [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Nek2A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Mus musculus)
Association of Cyclin A with the APC/C (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Degradation multiubiquitinated Cyclin A (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Mus musculus)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Mus musculus)
Association of Cdh1 with the APC/C (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Dissociation of Cdc20 from APC/C complex (Mus musculus)
CDC20:p-APC/C [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Regulation of APC/C activators between G1/S and early anaphase (Mus musculus)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Mus musculus)
Inactivation of APC/C via direct inhibition of the APC/C complex (Mus musculus)
Binding of the MCC complex to the APC/C complex (Mus musculus)
MCC:APC/C complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
S Phase (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
DNA Replication (Mus musculus)
Synthesis of DNA (Mus musculus)
Switching of origins to a post-replicative state (Mus musculus)
CDK-mediated phosphorylation and removal of Cdc6 (Mus musculus)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Mus musculus)
phospho-APC/C:Cdh1 complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen processing: Ubiquitination & Proteasome degradation (Mus musculus)
Interaction of E3 with substrate and E2-Ub complex (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Polyubiquitination of substrate (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
E3:K48-polyubiquitinated substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
E3:Ub:substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Release of E3 from polyubiquitinated substrate (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
E3:K48-polyubiquitinated substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
Transfer of Ub from E2 to substrate and release of E2 (Mus musculus)
Ag-substrate:E3:E2:Ub [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
E3:Ub:substrate [cytosol] (Mus musculus)
E3 ligases in proteasomal degradation [cytosol] (Mus musculus)
APC/C E3 ligase complex [cytosol] (Mus musculus)
Anapc5 [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q8BTZ4
Gene Names
Anapc5
Reference Genes
BioGPS Gene:59008 Anapc5
ENSEMBL:ENSMUSG00000029472
ENSEMBL:ENSMUSG00000029472.14 Anapc5
KEGG Gene (Mus musculus):59008 Anapc5
Monarch:59008 Anapc5
NCBI Gene:59008 Anapc5
UCSC:Q8BTZ4 Anapc5
Reference Transcript
RefSeq:NM_021505.3 Anapc5
RefSeq:NM_001042491.2 Anapc5
Other Identifiers
10533549
132437_s_at
1416906_at
1433822_x_at
1435177_a_at
1435178_x_at
1453307_a_at
1456695_x_at
17452477
4323231
4373729
4373903
4407482
4429453
4441524
4481739
4493480
4543426
4633838
4642450
4674003
4683217
4702478
4730004
4820025
4854783
5022581
5140667
5205070
5279402
5295424
5342718
5407010
5418474
5436794
5525098
59008
95100_at
A_52_P143847
A_55_P1952359
GE42818
GO:0000278
GO:0005515
GO:0005634
GO:0005680
GO:0005737
GO:0005819
GO:0005856
GO:0007049
GO:0007059
GO:0016567
GO:0019903
GO:0030163
GO:0031145
GO:0036211
GO:0043226
GO:0045842
GO:0051301
GO:0070979
GO:0140014
ILMN_2648397
ILMN_2738536
ILMN_3158200
aa271012_at
aa271012_g_at
mMC019995
Participates
as a component of
APC/C E3 ligase complex [cytosol] (Mus musculus)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Mus musculus)
Other forms of this molecule
Anapc5 [nucleoplasm]
Inferred From
ANAPC5 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_001035956.1
,
NP_067480.2
Ensembl
ENSMUST00000200645
,
ENSMUSG00000029472
,
ENSMUST00000086216
,
ENSMUSP00000083393
,
ENSMUSP00000142922
PRO
Q8BTZ4
MGI
1929722
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