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BAX activated [cytosol]
Stable Identifier
R-MMU-139907
Type
Protein [EntityWithAccessionedSequence]
Species
Mus musculus
Compartment
cytosol
Synonyms
Q07813
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Transcription of Cell Cycle Genes (Mus musculus)
TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest (Mus musculus)
SFN dimer binds BAX (Mus musculus)
BAX activated [cytosol] (Mus musculus)
SFN Dimer:BAX [cytosol] (Mus musculus)
BAX activated [cytosol] (Mus musculus)
Programmed Cell Death (Mus musculus)
Apoptosis (Mus musculus)
Intrinsic Pathway for Apoptosis (Mus musculus)
Activation, translocation and oligomerization of BAX (Mus musculus)
Translocation of activated BAX to the mitochondria (Mus musculus)
BAX activated [cytosol] (Mus musculus)
tBID activates BAX protein (Mus musculus)
BAX activated [cytosol] (Mus musculus)
tBID bound to inactive BAX [cytosol] (Mus musculus)
BAX activated [cytosol] (Mus musculus)
tBID binds to inactive BAX protein (Mus musculus)
BAX activated [cytosol] (Mus musculus)
tBID bound to inactive BAX [cytosol] (Mus musculus)
BAX activated [cytosol] (Mus musculus)
External Reference Information
External Reference
UniProt:Q07813
Reference Genes
BioGPS Gene:12028
dbSNP Gene:12028
ENSEMBL:ENSMUSG00000003873
ENSEMBL:ENSMUSG00000003873
KEGG Gene (Mus musculus):12028
Monarch:12028
NCBI Gene:12028
UCSC:Q07813
Reference Transcript
RefSeq:NM_007527.3
Other Identifiers
10563303
12028
1416837_at
17490839
203024
2XA0
4594740
4731712
4868174
5198086
5302632
5307337
5389642
5505507
5561168
5W62
93536_at
A0A1B0GT35
A0A1B0GT81
A0A1B0GTA4
A_55_P2137406
AAA03622
AAH18228
AAH53380
AK013298
AK149994
BAB28776
BAE29222
Bax
Bax-201
BC018228
BC053380
CCDS21246
CH466603
EDL22858
ENSMUSG00000003873
ENSMUSP00000033093
ENSMUST00000033093
EntrezGene:12028
EntrezGene:Bax
GO:0000003
GO:0001541
GO:0001764
GO:0001776
GO:0001777
GO:0001782
GO:0001783
GO:0001822
GO:0001836
GO:0001844
GO:0001974
GO:0002262
GO:0002352
GO:0002358
GO:0002376
GO:0002904
GO:0003674
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005635
GO:0005737
GO:0005739
GO:0005741
GO:0005757
GO:0005783
GO:0005789
GO:0005829
GO:0006091
GO:0006259
GO:0006464
GO:0006629
GO:0006687
GO:0006808
GO:0006810
GO:0006915
GO:0006919
GO:0006950
GO:0006974
GO:0007005
GO:0007007
GO:0007008
GO:0007049
GO:0007165
GO:0007281
GO:0007283
GO:0007399
GO:0007548
GO:0008053
GO:0008150
GO:0008219
GO:0008283
GO:0008285
GO:0008289
GO:0008584
GO:0008625
GO:0008630
GO:0008635
GO:0008637
GO:0009056
GO:0009566
GO:0009611
GO:0009636
GO:0009651
GO:0009790
GO:0009791
GO:0010212
GO:0010248
GO:0010332
GO:0010524
GO:0010917
GO:0015267
GO:0016020
GO:0016021
GO:0016032
GO:0021854
GO:0021987
GO:0022607
GO:0022857
GO:0030154
GO:0030544
GO:0031072
GO:0031966
GO:0032091
GO:0032461
GO:0032471
GO:0032976
GO:0032991
GO:0033137
GO:0033599
GO:0034641
GO:0034644
GO:0034655
GO:0035108
GO:0035234
GO:0040011
GO:0042475
GO:0042592
GO:0042802
GO:0042803
GO:0042981
GO:0043065
GO:0043226
GO:0043281
GO:0043473
GO:0043496
GO:0043497
GO:0043523
GO:0043524
GO:0043525
GO:0043653
GO:0044403
GO:0044877
GO:0045136
GO:0045333
GO:0046666
GO:0046930
GO:0046982
GO:0048087
GO:0048147
GO:0048471
GO:0048515
GO:0048597
GO:0048678
GO:0048856
GO:0048870
GO:0048872
GO:0048873
GO:0051087
GO:0051259
GO:0051260
GO:0051281
GO:0051400
GO:0051402
GO:0051434
GO:0051726
GO:0051881
GO:0055085
GO:0060011
GO:0060041
GO:0060058
GO:0060068
GO:0061024
GO:0065003
GO:0070059
GO:0070242
GO:0070584
GO:0071310
GO:0071944
GO:0072332
GO:0090200
GO:0097136
GO:0097144
GO:0097190
GO:0097191
GO:0097192
GO:0097193
GO:0097296
GO:1900103
GO:1902108
GO:1902110
GO:1902262
GO:1902263
GO:1902445
GO:1902512
GO:1990117
GO:2001234
GO:2001244
ILMN_2619295
ILMN_2907655
IPR002475
IPR020717
IPR020726
IPR020728
IPR026298
IPR026304
IPR036834
L22472
MGI:99702
mMC018736
Msa.126.0_s_at
NM_007527
NP_031553
PF00452
PR01862
Q544Z6
SM00337
uc009gvi.1
UPI0000001972
XM_011250780
XP_011249082
Participant Of
input
SFN dimer binds BAX
tBID binds to inactive BAX protein
Translocation of activated BAX to the mitochondria
hasComponent
SFN Dimer:BAX [cytosol]
tBID bound to inactive BAX [cytosol]
output
tBID activates BAX protein
Other forms of this molecule
BAX [mitochondrial outer membrane]
Inferred From
BAX [cytosol] (Homo sapiens)
BAX activated [cytosol] (Homo sapiens)
Cross References
RefSeq
NP_031553.1
PRO
Q07813
PDB
5W62
,
2XA0
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P10417
1
BCL2 [mitochondrial outer membrane]
(R-MMU-50757)
0.573
2
UniProt:P21796 VDAC1
4
VDAC1 [mitochondrial outer membrane]
(R-HSA-1267988)
K48polyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-5205624)
PolyUb-VDAC1 [mitochondrial outer membrane]
(R-HSA-6783079)
VDAC1 [mitochondrial intermembrane space]
(R-HSA-1267960)
0.544
2
UniProt:O75460 ERN1
2
ERN1 [endoplasmic reticulum membrane]
(R-HSA-381076)
p-S724-ERN1 [endoplasmic reticulum membrane]
(R-HSA-381029)
0.524
2
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