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DTX3L [cytosol]
Stable Identifier
R-HSA-975994
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
E3 ubiquitin-protein ligase DTX3L, DTX3L_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
DTX3L [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
DTX3L [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
DTX3L [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
DTX3L [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
DTX3L [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
DTX3L [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
DTX3L [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
DTX3L [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
DTX3L [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
DTX3L [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q8TDB6 DTX3L
Gene Names
DTX3L, BBAP
Chain
initiator methionine:, chain:2-740
Reference Genes
BioGPS Gene:151636 DTX3L
COSMIC (genes):DTX3L DTX3L
CTD Gene:151636 DTX3L
dbSNP Gene:151636 DTX3L
ENSEMBL:ENSG00000163840 DTX3L
ENSEMBL_homo_sapiens_GENE:ENSG00000163840.10 DTX3L
HGNC:30323 DTX3L
Monarch:151636 DTX3L
NCBI Gene:151636 DTX3L
OMIM:613143 DTX3L
UCSC:Q8TDB6 DTX3L
Reference Transcript
RefSeq:NM_138287.3 DTX3L
Other Identifiers
11717561_s_at
11717562_x_at
11717563_a_at
151636
16944665
225415_PM_at
225415_at
2638963
2638964
2638965
2638967
2638968
2638969
2638970
2638971
2638972
2638973
2638975
2638976
2638979
2638980
2638981
2638982
2638987
2638989
2638990
2638991
2638992
2638993
44718_at
8082075
A_14_P110980
A_23_P347040
A_24_P941912
GE568798
GO:0000077
GO:0002230
GO:0002376
GO:0003824
GO:0004842
GO:0004857
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005769
GO:0005773
GO:0005829
GO:0006281
GO:0006302
GO:0006325
GO:0006351
GO:0006355
GO:0006511
GO:0006974
GO:0007219
GO:0008333
GO:0015031
GO:0016020
GO:0016192
GO:0016567
GO:0016740
GO:0019899
GO:0023052
GO:0030163
GO:0031410
GO:0031901
GO:0032092
GO:0032991
GO:0035563
GO:0036211
GO:0042393
GO:0043226
GO:0044389
GO:0045087
GO:0045893
GO:0046872
GO:0051444
GO:0051607
GO:0051865
GO:0060090
GO:0070936
GO:0097677
GO:0098542
GO:0098772
GO:0140096
GO:0140768
GO:0140852
GO:0140861
GO:0141000
GO:1900182
GO:1902966
GO:2000646
HMNXSV003002457
Hs.16331.0.S1_3p_at
ILMN_1784380
PH_hs_0016489
TC03000632.hg
Participates
as a member of
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
Inferred To
Dtx3l [cytosol]
(Mus musculus)
Dtx3l [cytosol]
(Rattus norvegicus)
DTX3L [cytosol]
(Bos taurus)
DTX3L [cytosol]
(Canis familiaris)
DTX3L [cytosol]
(Gallus gallus)
DTX3L [cytosol]
(Sus scrofa)
si:ch73-78o10.1 [cytosol]
(Danio rerio)
Cross References
RefSeq
NP_612144.1
OpenTargets
ENSG00000163840
IntEnz
2.3.2.27
HPA
ENSG00000163840-DTX3L
GeneCards
Q8TDB6
Ensembl
ENST00000383661
,
ENST00000296161
,
ENSG00000163840
,
ENSP00000296161
,
ENSP00000373157
PRO
Q8TDB6
Pharos - Targets
Q8TDB6
PDB
3PG6
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