Reactome | Ac-55-DUSP16 [cytosol]

Ac-55-DUSP16 [cytosol]

Stable Identifier

R-HSA-9636576

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

N6-acetyl-L-Lys 55 DUSP16

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Bacterial Infection Pathways (Homo sapiens)
    - Infection with Mycobacterium tuberculosis (Homo sapiens)
      - Response of Mtb to phagocytosis (Homo sapiens)
        
        Suppression of autophagy (Homo sapiens)
        
        Eis acetylates DUSP16 (Homo sapiens)
        
        Ac-55-DUSP16 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9BY84 DUSP16

Gene Names

DUSP16, KIAA1700, MKP7

Chain

chain:1-665

Reference Genes

BioGPS Gene:80824 DUSP16

COSMIC (genes):DUSP16 DUSP16

CTD Gene:80824 DUSP16

dbSNP Gene:80824 DUSP16

ENSEMBL:ENSG00000111266 DUSP16

ENSEMBL_homo_sapiens_GENE:ENSG00000111266.9 DUSP16

ENSEMBL_homo_sapiens_GENE:ENSG00000280962.3 DUSP16

HGNC:17909 DUSP16

KEGG Gene (Homo sapiens):80824 DUSP16

Monarch:80824 DUSP16

NCBI Gene:80824 DUSP16

OMIM:607175 DUSP16

UCSC:Q9BY84 DUSP16

Reference Transcript

Other Identifiers

11723316_a_at

11752504_a_at

11764149_s_at

1555399_PM_a_at

1555399_a_at

16761631

224336_PM_s_at

224336_s_at

224832_PM_at

224832_at

3444959

3444960

3444961

3444962

3444963

3444964

3444965

3444966

3444967

3444969

3444976

3444977

3444979

3444980

3444984

3444986

3444987

3444999

3445003

54875_at

56263_at

7961371

80824

A_23_P308924

A_23_P353905

A_24_P189739

A_24_P73264

GE567921

GE61015

GO:0003824

GO:0004721

GO:0004722

GO:0004725

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006470

GO:0006886

GO:0006913

GO:0008138

GO:0008330

GO:0008432

GO:0016311

GO:0016787

GO:0016791

GO:0017017

GO:0017018

GO:0023052

GO:0031410

GO:0033550

GO:0036211

GO:0043226

GO:0043409

GO:0043508

GO:0045204

GO:0048273

GO:0051019

GO:0140096

HMNXSV003025167

Hs.20281.0.S2_3p_at

Hs2.20281.2.S1_3p_s_at

ILMN_1764361

PH_hs_0001766

TC12001255.hg

g13548676_3p_s_at

Participates

as an output of

Eis acetylates DUSP16 (Homo sapiens)

Other forms of this molecule

DUSP16 [cytosol]

DUSP16 [nucleoplasm]

Modified Residues

Name

N6-acetyl-L-lysine at 55

Coordinate

PsiMod Name

N6-acetyl-L-lysine [MOD:00064]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.

Cross References

RefSeq

NP_085143.1, XP_006719218.1, XP_011519158.1, XP_011519159.1

OpenTargets

ENSG00000111266

IntEnz

3.1.3.48

GeneCards

Q9BY84

HPA

ENSG00000111266-DUSP16

Ensembl

ENST00000628303, ENST00000626413, ENST00000228862, ENSG00000280962, ENSP00000487512, ENST00000298573, ENSG00000111266, ENSP00000487034, ENSP00000228862, ENSP00000298573

PRO

Q9BY84

Pharos - Targets

Q9BY84

HMDB Protein

HMDBP08906

PDB

3TG3, 2VSW, 4YR8

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P45984 MAPK9	3	MAPK9 [cytosol] (R-HSA-450355) p-T183,Y185-MAPK9 [cytosol] (R-HSA-450293) p-T183,Y185-MAPK9 [nucleoplasm] (R-HSA-450319)	0.742	7
UniProt:P45983-4 MAPK8			0.556	3
UniProt:O76024 WFS1	3	WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747) p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474)	0.556	3
UniProt:Q16539 MAPK14	7	MAPK14 [secretory granule lumen] (R-HSA-6803300) MAPK14 [extracellular region] (R-HSA-6806453) MAPK14 [ficolin-1-rich granule lumen] (R-HSA-6803280) MAPK14 [nucleoplasm] (R-HSA-446223) MAPK14 [cytosol] (R-HSA-428933) p-T180,Y182-MAPK14 [cytosol] (R-HSA-428935) p-T180,Y182-MAPK14 [nucleoplasm] (R-HSA-446227)	0.547	2