Reactome | PIN1 [cytosol]

PIN1 [cytosol]

Stable Identifier

R-HSA-9626823

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, PIN1_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q9UKD1 GMEB2

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External Reference Information

External Reference

UniProt:Q13526 PIN1

Gene Names

PIN1

Chain

chain:1-163

Reference Genes

BioGPS Gene:5300 PIN1

COSMIC (genes):PIN1 PIN1

CTD Gene:5300 PIN1

dbSNP Gene:5300 PIN1

ENSEMBL:ENSG00000127445 PIN1

HGNC:8988 PIN1

KEGG Gene (Homo sapiens):5300 PIN1

Monarch:5300 PIN1

NCBI Gene:5300 PIN1

OMIM:601052 PIN1

UCSC:Q13526 PIN1

Reference Transcript

RefSeq:NM_006221.3 PIN1

Other Identifiers

11744155_x_at

11751059_x_at

1F8A

1I6C

1I8G

1I8H

1NMV

1NMW

1PIN

1ZCN

202927_3p_at

202927_at

2F21

2ITK

2KBU

2KCF

2LB3

2M8I

2M8J

2M9E

2M9F

2M9I

2M9J

2N1O

2Q5A

2RUC

2RUD

2RUQ

2RUR

2XP3

2XP4

2XP5

2XP6

2XP7

2XP8

2XP9

2XPA

2XPB

2ZQS

2ZQT

2ZQU

2ZQV

2ZR4

2ZR5

2ZR6

3820179

3820189

3820196

3820201

3820202

3820203

3820204

3I6C

3IK8

3IKD

3IKG

3JYJ

3KAB

3KAC

3KAD

3KAF

3KAG

3KAH

3KAI

3KCE

3NTP

3ODK

3OOB

3TC5

3TCZ

3TDB

3WH0

40421_at

4528

4GWT

4GWV

4QIB

4TNS

4TYO

4U84

4U85

4U86

5300

5B3W

5B3X

5B3Y

5B3Z

5BMY

5GPH

5UY9

5VTI

5VTJ

5VTK

68650

6DUN

8025506

9326

A_23_P67162

A_33_P3210168

AAC50492

AAH02899

AAV38138

AK291074

BAF83763

BC002899

BT019331

CAB004528

CAB009326

CAG28582

CCDS12220

CH471106

CR407654

EAW84057

ENSG00000127445

ENSP00000247970

ENSP00000466962

ENST00000247970

ENST00000247970.8

ENST00000588695

ENST00000588695.5

ENST00000590540

EntrezGene:5300

EntrezGene:PIN1

g5453897_3p_at

g5453897_3p_s_at

g5453897_3p_x_at

GE59199

GO:0000278

GO:0000413

GO:0001666

GO:0001932

GO:0001934

GO:0003674

GO:0003755

GO:0003774

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005737

GO:0005739

GO:0005829

GO:0006464

GO:0006950

GO:0007049

GO:0007088

GO:0007165

GO:0007267

GO:0008013

GO:0008092

GO:0008150

GO:0008219

GO:0009056

GO:0009058

GO:0010468

GO:0016607

GO:0016853

GO:0016859

GO:0019899

GO:0030154

GO:0030182

GO:0030496

GO:0030512

GO:0031434

GO:0031647

GO:0032091

GO:0032092

GO:0032465

GO:0032480

GO:0032794

GO:0034641

GO:0035307

GO:0040007

GO:0040011

GO:0042177

GO:0043005

GO:0043226

GO:0043524

GO:0043525

GO:0043547

GO:0045944

GO:0048156

GO:0048856

GO:0048870

GO:0050808

GO:0050815

GO:0050816

GO:0050821

GO:0051219

GO:0051301

GO:0051443

GO:0060393

GO:0061051

GO:0070373

GO:0090263

GO:0098978

GO:0099524

GO:0140014

GO:1900180

GO:1901796

GO:1902430

GO:2000146

HGNC:8988

HPA068650

ILMN_1776375

IPR000297

IPR001202

IPR023058

IPR036020

K7EMU7

LRG_847

LRG_847t1

MIM:601052

NM_006221

NP_006212

PF00397

PF00639

PH_hs_0033354

PIN1

PIN1-201

PIN1-207

SM00456

TC19001974.hg

U49070

U49070_at

UPI000004062D

XM_011528068

XP_011526370

Participant Of

hasComponent

input

PIN1 binds p-S345-NCF1

Other forms of this molecule

PIN1 [nucleoplasm]

Inferred To

PIN1 [cytosol] (Bos taurus)

PIN1 [cytosol] (Canis familiaris)

PIN1 [cytosol] (Danio rerio)

PIN1 [cytosol] (Gallus gallus)

PIN1 [cytosol] (Mus musculus)

PIN1 [cytosol] (Rattus norvegicus)

PIN1 [cytosol] (Saccharomyces cerevisiae)

PIN1 [cytosol] (Schizosaccharomyces pombe)

PIN1 [cytosol] (Sus scrofa)

PIN1 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_006212.1

OpenTargets

ENSG00000127445

IntEnz

5.2.1.8

ZINC - Substances

PIN1_HUMAN

GeneCards

Q13526

ZINC target

Q13526

PRO

Q13526

ZINC - Predictions - Purchasable

PIN1_HUMAN

PDB

2KCF, 1I6C, 5B3Y, 3IK8, 2XP6, 5B3Z, 4TNS, 2RUR, 5VTI, 5B3X, 2ZQS, 2Q5A, 2XP7, 3KAB, 6DUN, 4U84, 2XP8, 5B3W, 2ZQT, 2LB3, 3KAC, 3NTP, 5VTK, 4GWT, 3IKD, 4QIB, 2XP9, 3KCE, 3JYJ, 3I6C, 2ZQU, 3IKG, 3TC5, 3KAD, 5VTJ, 5UY9, 4U86, 1ZCN, 2RUC, 5BMY, 2ZQV, 3OOB, 1NMV, 3KAF, 3TCZ, 1I8G, 4U85, 2RUD, 2M8I, 2XPB, 2M9E, 2M9F, 1NMW, 3KAG, 2XPA, 2ZR4, 2N1O, 4GWV, 1I8H, 3TDB, 5GPH, 2XP4, 2M8J, 2XP3, 2ZR5, 1PIN, 3KAH, 2KBU, 4TYO, 1F8A, 3ODK, 2F21, 2M9I, 2XP5, 2M9J, 2ZR6, 2ITK, 3WH0, 3KAI, 2RUQ

Interactors (156)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P04637 TP53	27	TP53 [cytosol] (R-HSA-8869337) Unfolded TP53 [cytosol] (R-HSA-6813797) PolyUb-TP53 [nucleoplasm] (R-HSA-6782509) SUMO2,3-K386-TP53 [nucleoplasm] (R-HSA-2997661) Me2K-370,382-TP53 [nucleoplasm] (R-HSA-3222242) PolyUb,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6804446) p-T55-TP53 [nucleoplasm] (R-HSA-6805400) p-S15,S20,S392-TP53 [nucleoplasm] (R-HSA-6805053) p-S315-TP53 [nucleoplasm] (R-HSA-6805106) p-S15,S20,S269,T284-TP53 [nucleoplasm] (R-HSA-6805133) p-S15,S20,S46-TP53 [nucleoplasm] (R-HSA-6798369) p-S15,S33,S46-TP53 [nucleoplasm] (R-HSA-6805268) p-S37-TP53 [nucleoplasm] (R-HSA-3239022) p-S15,S392-TP53 [nucleoplasm] (R-HSA-3222015) Me1-K372,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805719) Me-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222124) MeK-370,p-S15,S20-TP53 [nucleoplasm] (R-HSA-3222226) p-S15,S20,Me-R333,Me2-R335,R337-TP53 [nucleoplasm] (R-HSA-6804378) Me2-K373-TP53 [nucleoplasm] (R-HSA-6805759) Ac-K120,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805656) Ac-K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-5628868) Ac-K120,K382,p-S15,S20-TP53 [nucleoplasm] (R-HSA-6805631) PolyUb-TP53 [nucleoplasm] (R-HSA-6793679) PolyUb-TP53 [cytosol] (R-HSA-6793681) p-S15,S20-TP53 [nucleoplasm] (R-HSA-69683) p-S15-TP53 [nucleoplasm] (R-HSA-69507) TP53 [nucleoplasm] (R-HSA-69488)	0.846	14
UniProt:Q9Y3Q8 T22D4			0.764	6
UniProt:Q15025 TNIP1	1	TNIP1 [cytosol] (R-HSA-5690853)	0.764	6
UniProt:Q99750 MDFI			0.764	6
UniProt:Q12933 TRAF2	5	K63polyUb-TRAF2 [nucleoplasm] (R-HSA-8862194) TRAF2 [nucleoplasm] (R-HSA-8862199) K63polyUb-TRAF2 [cytosol] (R-HSA-8862193) TRAF2 [cytosol] (R-HSA-66370) PolyUb-TRAF2 [cytosol] (R-HSA-6782848)	0.764	6
UniProt:P01106 MYC	2	PolyUb-MYC [nucleoplasm] (R-HSA-6783169) MYC [nucleoplasm] (R-HSA-188379)	0.71	5
UniProt:Q9BWW4 SSBP3			0.696	5
UniProt:P37198 NUP62	1	NUP62 [nuclear envelope] (R-HSA-157713)	0.696	5
UniProt:Q969H4 CNKSR1	1	CNKSR1 [cytosol] (R-HSA-5672629)	0.696	5
UniProt:Q15323 KRT31	1	KRT31 [cytosol] (R-HSA-6809616)	0.696	5
UniProt:Q52MB2 CC184			0.696	5
UniProt:Q9NWS9-2 ZNF446			0.696	5
UniProt:Q8TAP6 CEP76	1	CEP76 [cytosol] (R-HSA-380281)	0.696	5
UniProt:Q96C00 ZBTB9			0.696	5
UniProt:O15409 FOXP2			0.696	5
UniProt:Q9UKT9 IKZF3			0.696	5
UniProt:O76015 KRT38	1	KRT38 [cytosol] (R-HSA-6809615)	0.696	5
UniProt:Q6AI12 ANR40			0.696	5
UniProt:Q96MH2 HEXI2			0.696	7
UniProt:Q15742 NAB2			0.696	5
UniProt:Q08379 GOLGA2	3	GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.696	5
UniProt:P85298-4 ARHGAP8			0.672	25
UniProt:Q93062 RBPMS			0.666	4
UniProt:P35520 CBS	1	PXLP-K119-CBS [cytosol] (R-HSA-1614563)	0.666	4
UniProt:Q15233 NONO			0.666	4
UniProt:Q9BT49 THAP7			0.666	5
UniProt:Q8NF64 ZMIZ2			0.666	4
UniProt:Q96AA8 JKIP2			0.666	4
UniProt:Q7Z5J4 RAI1	1	RAI1 [nucleoplasm] (R-HSA-5656531)	0.666	4
UniProt:P41279 MAP3K8	4	MAP3K8 [cytosol] (R-HSA-389388) p-S400,T290-MAP3K8 [cytosol] (R-HSA-5684259) p-S400-MAP3K8 [cytosol] (R-HSA-5684308) p-S400-MAP3K8 [cytosol] (R-HSA-389738)	0.66	8
UniProt:P51617 IRAK1	14	p-S,T-IRAK1 [cytosol] (R-HSA-3149574) K63polyUb-hp-IRAK1 [endosome membrane] (R-HSA-975112) p-S376,T387-IRAK1 [cytosol] (R-HSA-446687) K63polyUb-hp-IRAK1 [cytosol] (R-HSA-451565) IRAK1 [cytosol] (R-HSA-446639) p-2S,S376,T,T209,T387-IRAK1 [cytosol] (R-HSA-446682) p-2S,S376,T,T209,T387-IRAK1 [plasma membrane] (R-HSA-937011) p-T209,T387-IRAK1 [plasma membrane] (R-HSA-166279) p-T209-IRAK1 [plasma membrane] (R-HSA-937031) IRAK1 [plasma membrane] (R-HSA-937045) p-2S,S376,T,T209,T387-IRAK1 [endosome membrane] (R-HSA-975157) p-T209,T387-IRAK1 [endosome membrane] (R-HSA-975117) p-T209-IRAK1 [endosome membrane] (R-HSA-975189) IRAK1 [endosome membrane] (R-HSA-975127)	0.645	10
UniProt:Q63932	3	phospho-p-S222,S226-MAP2K2 [cytosol] (R-MMU-169292) MAP2K2 [cytosol] (R-MMU-59504) phospho-p-S,T-MAP2K2 [cytosol] (R-MMU-109848)	0.628	12
UniProt:Q9BWG4 SSBP4			0.621	3
UniProt:O00267 SUPT5H	1	p-SUPT5H [nucleoplasm] (R-HSA-3009372)	0.621	3
UniProt:Q13342 SP140			0.611	4
IntAct:EBI-10173330 386677			0.601	4
UniProt:P46531 NOTCH1	60	NOTCH1 I1680N S2 cleavage fragment [extracellular region] (R-HSA-2730744) NOTCH1 L1678P S2 cleavage fragment [extracellular region] (R-HSA-2730745) NOTCH1 I1718T S2 cleavage fragment [extracellular region] (R-HSA-2730757) NOTCH1 A1701P S2 cleavage fragment [plasma membrane] (R-HSA-2730742) NOTCH1 V1676D S2 cleavage fragment [extracellular region] (R-HSA-2730755) NOTCH1 I1680N Transmembrane Fragment [plasma membrane] (R-HSA-2684869) NOTCH1 I1718T Transmembrane Fragment [plasma membrane] (R-HSA-2684881) NOTCH1 I1616T Extracellular Fragment [extracellular region] (R-HSA-2684866) NOTCH1 L1596H Extracellular Fragment [extracellular region] (R-HSA-2684853) NOTCH1 L1678P Transmembrane Fragment [plasma membrane] (R-HSA-1485591) NOTCH1 A1701P Transmembrane Fragment [plasma membrane] (R-HSA-1485585) NOTCH1 I1616N Extracellular Fragment [extracellular region] (R-HSA-2684862) NOTCH1 L1593P Extracellular Fragment [extracellular region] (R-HSA-1485584) NOTCH1 R1598P Extracellular Fragment [extracellular region] (R-HSA-1485592) NOTCH1 V1576E Extracellular Fragment [extracellular region] (R-HSA-2684852) NOTCH1 V1676D Transmembrane Fragment [plasma membrane] (R-HSA-2684874) NOTCH1 F1592S Extracellular Fragment [extracellular region] (R-HSA-2684847) NOTCH1 L1574Q Extracellular Fragment [extracellular region] (R-HSA-2691203) p-NICD1 Q2440* [nucleoplasm] (R-HSA-2902207) p-NICD1 Q2395* [nucleoplasm] (R-HSA-2902205) p-NICD1 P2514Rfs4 [nucleoplasm] (R-HSA-2159809) p-NICD1 P2474Afs4 [nucleoplasm] (R-HSA-2902204) NOTCH1 L1574P Extracellular Fragment [extracellular region] (R-HSA-1485582) NOTCH1 L1600P Extracellular Fragment [extracellular region] (R-HSA-2681764) NEXT1 P2474Afs4 [plasma membrane] (R-HSA-2902194) NEXT1 Q2395 [plasma membrane] (R-HSA-2902192) NEXT1 Q2440* [plasma membrane] (R-HSA-2902196) NEXT1 P2514Rfs4 [plasma membrane] (R-HSA-2768989) NICD1 Q2395 [cytosol] (R-HSA-2902195) NICD1 P2514Rfs4 [cytosol] (R-HSA-2768996) NICD1 P2474Afs4 [cytosol] (R-HSA-2902193) NICD1 Q2440* [cytosol] (R-HSA-2902191) NICD1 P2514Rfs4 [nucleoplasm] (R-HSA-2769013) NICD1 P2474Afs4 [nucleoplasm] (R-HSA-2902208) NICD1 Q2395* [nucleoplasm] (R-HSA-2902201) NICD1 Q2440* [nucleoplasm] (R-HSA-2902200) NOTCH1 P2514Rfs4 Transmembrane Fragment [plasma membrane] (R-HSA-2768982) NOTCH1 Q2395 Transmembrane Fragment [plasma membrane] (R-HSA-1485596) NOTCH1 Q2440* Transmembrane Fragment [plasma membrane] (R-HSA-1485602) NOTCH1 P2474Afs*4 Transmembrane Fragment [plasma membrane] (R-HSA-2894873) NOTCH1 t(7;9)(NOTCH1:M1580_K2555) extracellular fragment [extracellular region] (R-HSA-2220929) p-NICD1 [nucleoplasm] (R-HSA-1604444) Glc,GlcNAc-Fuc-Pre-NOTCH1 [Golgi membrane] (R-HSA-1911426) Glc,Gal-GlcNAc-Fuc-Pre-NOTCH1 [Golgi membrane] (R-HSA-1911415) Glc,Sia-Gal-GlcNAc-Fuc-Pre-NOTCH1 [Golgi membrane] (R-HSA-1911503) FRINGE-modified NOTCH1 Extracellular Fragment (NECD1) [Golgi membrane] (R-HSA-1911511) Pre-NOTCH1 [endoplasmic reticulum membrane] (R-HSA-157024) 17xFucT-2xFucS-NOTCH1(19-2555) [endoplasmic reticulum membrane] (R-HSA-1467396) 19xFucT-14xGlcS-2xFucS-NOTCH1(19-2555) [endoplasmic reticulum membrane] (R-HSA-1467425) 17xFucT-14xGlcS-2xFucS-NOTCH1(19-2555) [Golgi membrane] (R-HSA-1472872) NOTCH1(1665-2555) [Golgi membrane] (R-HSA-157092) 17xFucT-14xGlcS-2xFucS-NOTCH1(19-1664) [Golgi membrane] (R-HSA-1983679) FRINGE-modified NOTCH1 Extracellular Fragment (NECD1) [plasma membrane] (R-HSA-1911512) NOTCH1(1665-2555) [plasma membrane] (R-HSA-157239) 19xFucT-16xGlcS-2xFucS-NOTCH1(19-1664) [extracellular region] (R-HSA-1983670) NOTCH1(1665-1720) [extracellular region] (R-HSA-157654) NOTCH1(1721-1753) [plasma membrane] (R-HSA-157656) NEXT1 [plasma membrane] (R-HSA-157200) NICD1 [nucleoplasm] (R-HSA-157939) NICD1 [cytosol] (R-HSA-157634)	0.591	9
UniProt:Q15131 CDK10			0.591	5
UniProt:Q13950 RUNX2			0.591	7
UniProt:Q9BR01 SULT4A1	1	SULT4A1 [cytosol] (R-HSA-176668)	0.581	4
UniProt:P78563 ADARB1	1	ADARB1 [nucleoplasm] (R-HSA-62915)	0.571	12
UniProt:P04049 RAF1	10	p-S338,Y340,Y341-RAF1 [cytosol] (R-HSA-5624465) RAF1 [cytosol] (R-HSA-167205) p-S338-RAF1 [cytosol] (R-HSA-5624469) p-S259,S621-RAF1 [cytosol] (R-HSA-109786) p-S621-RAF1 [plasma membrane] (R-HSA-206222) hyperphosphorylated RAF1 [plasma membrane] (R-HSA-5675193) p-Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5675420) p-S621-RAF1 [cytosol] (R-HSA-206028) p-S338,Y341,T491,S494,S621 RAF1 [plasma membrane] (R-HSA-5672665) p-S338,Y341,T491,S494,S621 RAF1 [cytosol] (R-HSA-5672664)	0.564	2
UniProt:P31938 Map2k1	5	phospho-p-S218,S222,T286,T292-MAP2K1 [cytosol] (R-MMU-112339) phospho-p-S,218, S222,T292 MAP2K1 [cytosol] (R-MMU-5674490) phospho-p-T286,T292-MAP2K1 [cytosol] (R-MMU-112374) Mek1 [cytosol] (R-MMU-451658) Phospho Mek1 [cytosol] (R-MMU-451693)	0.558	4
UniProt:Q99708-2 RBBP8			0.556	3
UniProt:Q8N5C8 TAB3	3	TAB3 [plasma membrane] (R-HSA-446879) TAB3 [endosome membrane] (R-HSA-450247) TAB3 [cytosol] (R-HSA-450264)	0.556	3
UniProt:Q9BYR5 KRTAP4-2	1	KRTAP4-2 [cytosol] (R-HSA-6809948)	0.556	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3
UniProt:Q8ND90 PNMA1			0.556	3
IntAct:EBI-10171679 386682			0.556	3
UniProt:Q6UY14-3 ADAMTSL4			0.556	3
UniProt:Q13422 IKZF1			0.556	3
UniProt:O75553 DAB1	2	p-Y198,220,232-DAB1 [cytosol] (R-HSA-8855227) DAB1 [cytosol] (R-HSA-8855236)	0.556	3
UniProt:Q4VCS5-2 AMOT			0.556	3
UniProt:Q15654 TRIP6			0.556	3
UniProt:Q13077 TRAF1	3	TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1 [cytosol] (R-HSA-5634163) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.556	3
UniProt:Q5JR59 MTUS2			0.556	3
UniProt:Q8NF64-2 ZMIZ2			0.556	3
IntAct:EBI-10171584 80125			0.556	3
UniProt:Q53EZ4 CEP55			0.556	3
UniProt:Q9NYB9 ABI2	2	ABI2 [cytosol] (R-HSA-1671647) p-4S-ABI2 [cytosol] (R-HSA-2029003)	0.556	3
UniProt:Q15233-2 NONO			0.556	3
UniProt:Q96M27 PRRC1			0.556	3
UniProt:O43829 ZBT14			0.556	3
UniProt:Q9HC98 NEK6	2	NEK6 [cytosol] (R-HSA-2530596) p-S206-NEK6 [cytosol] (R-HSA-2984253)	0.556	3
UniProt:Q8IX15-3 HOMEZ			0.556	3
UniProt:O15209 ZBT22			0.556	3
UniProt:P15884 TCF4	1	TCF4 [nucleoplasm] (R-HSA-445672)	0.556	3
UniProt:P60411 KRTAP10-9	1	KRTAP10-9 [cytosol] (R-HSA-6810277)	0.556	3
UniProt:Q8NA61 SPERT			0.556	3
UniProt:Q6A162 KRT40	1	KRT40 [cytosol] (R-HSA-6809605)	0.556	3
UniProt:O15156 ZBT7B			0.556	3
UniProt:P50222 MEOX2			0.556	3
UniProt:D3DTR7 D3DTR7			0.556	3
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.544	2
UniProt:Q3UVX5	1	GRM5 [plasma membrane] (R-MMU-420553)	0.544	2
UniProt:P31424-2 GRM5			0.524	3
UniProt:Q02750 MAP2K1	7	MAP2K1(2-8) [cytosol] (R-HSA-5211342) MAP2K1(9-393) [cytosol] (R-HSA-5211353) p-S,218, S222,T292 MAP2K1 [cytosol] (R-HSA-5674490) p-T286,T292-MAP2K1 [cytosol] (R-HSA-112374) p-S218,S222,T286,T292-MAP2K1 [cytosol] (R-HSA-112339) MAP2K1 [cytosol] (R-HSA-59502) p-S218,S222-MAP2K1 [cytosol] (R-HSA-109837)	0.508	5
UniProt:Q99728-1 BARD1			0.499	4
UniProt:Q9H165-2 BCL11A			0.488	2
UniProt:Q16254 E2F4	1	E2F4 [nucleoplasm] (R-HSA-68664)	0.488	2
UniProt:Q9BTY2 FUCA2	4	FUCA2 [azurophil granule lumen] (R-HSA-6798772) FUCA2 [extracellular region] (R-HSA-6806227) p-FUCA2 [endoplasmic reticulum lumen] (R-HSA-8957005) FUCA2 [endoplasmic reticulum lumen] (R-HSA-8956727)	0.488	2
UniProt:Q8NC74 RB8NL			0.488	2
UniProt:Q96MP8-2 KCTD7			0.488	2
UniProt:Q5JR59-3 MTUS2			0.488	2
UniProt:Q03989 ARI5A			0.488	2
UniProt:P41212 ETV6			0.488	2
UniProt:Q9NR12 PDLIM7	1	PDLIM7 [cytosol] (R-HSA-8855085)	0.488	2
UniProt:Q5TD97 FHL5			0.488	2
IntAct:EBI-11957986 HOMEZ			0.488	2
UniProt:KRTAP10-7 P60409-2			0.488	2
UniProt:Q12951-2 FOXI1			0.488	2
UniProt:Q8NA61-2 SPERT			0.488	2
UniProt:A6NC98 CC88B			0.488	2
IntAct:EBI-11522976 CCDC33			0.488	2
IntAct:EBI-12063065 TOX3			0.488	2
UniProt:P0C1Z6 TFPT	1	TFPT [nucleoplasm] (R-HSA-5689542)	0.488	2
UniProt:Q8N9R8 SCAI	1	SCAI [nucleoplasm] (R-HSA-5666012)	0.488	2
UniProt:Q14CS0 UBX2B			0.488	2
UniProt:Q9UKD1 GMEB2			0.488	2
UniProt:P14373 TRIM27	2	TRIM27 [nucleoplasm] (R-HSA-2997690) TRIM27 [cytosol] (R-HSA-8851002)	0.488	2
UniProt:O00167-2 EYA2			0.488	2
UniProt:O76011 KRT34	1	KRT34 [cytosol] (R-HSA-6809608)	0.488	2
UniProt:Q9UPG8 PLAL2			0.488	2
UniProt:Q6FHY5 Q6FHY5			0.488	2
UniProt:O76014 KRT37	1	KRT37 [cytosol] (R-HSA-6809614)	0.488	2
UniProt:Q86V38 Q86V38			0.488	2
UniProt:O15353 FOXN1			0.488	2
UniProt:Q9H5H4 ZN768			0.488	2
UniProt:Q8NF64-3 ZMIZ2			0.488	2
UniProt:Q9H3D4 TP63	1	TP63 [nucleoplasm] (R-HSA-2997585)	0.488	2
UniProt:A6NEM1 GG6L9			0.488	2
UniProt:B4DUY5 B4DUY5			0.488	2
UniProt:B2RXF5 ZBT42			0.488	2
UniProt:Q13422-7 IKZF1			0.488	2
UniProt:A1L4H1 SSC5D	1	SSC5D [extracellular region] (R-HSA-8878615)	0.488	2
UniProt:Q63HR2 TNS2			0.488	2
UniProt:Q9NYB9-2 ABI2			0.488	2
UniProt:Q9UHD9 UBQLN2	1	UBQLN2 [cytosol] (R-HSA-8866007)	0.488	2
UniProt:P26371 KRTAP5-9	1	KRTAP5-9 [cytosol] (R-HSA-6810265)	0.488	2
UniProt:Q96KG9-4 SCYL1			0.488	2
UniProt:Q8TDT2 GP152			0.488	2
UniProt:Q8NBZ0 INO80E	1	INO80E [nucleoplasm] (R-HSA-5689552)	0.488	2
UniProt:Q16204 CCDC6			0.488	4
UniProt:Q494R4-2 CCDC153			0.488	2
UniProt:P08151 GLI1	9	GLI1 [ciliary base] (R-HSA-5610357) GLI1 [ciliary tip] (R-HSA-5610360) p-GLI1 [nucleoplasm] (R-HSA-5635042) 2p-GLI1 [nucleoplasm] (R-HSA-5635057) p-GLI1 [ciliary tip] (R-HSA-5635040) GLI1 [cytosol] (R-HSA-445457) pS-GLI1 [ciliary base] (R-HSA-5610497) ub-pS-GLI1 [ciliary base] (R-HSA-5610514) ub-GLI1 [cytosol] (R-HSA-5635833)	0.488	2
UniProt:P80188 LCN2	2	LCN2 [extracellular region] (R-HSA-5215934) LCN2 [specific granule lumen] (R-HSA-6799614)	0.488	2
UniProt:Q8NAP8 ZBT8B			0.488	2
UniProt:Q6P9G9 ZN449			0.488	2
UniProt:Q92570 NR4A3	1	NR4A3 [nucleoplasm] (R-HSA-8938004)	0.488	2
UniProt:P59797 SELV			0.488	2
UniProt:Q8NFW5 DMBX1			0.488	2
UniProt:A0A384NQ31 A0A384NQ31			0.488	2
UniProt:Q3SXR2 CC036			0.488	2
UniProt:Q6ZMS7-2 Q6ZMS72			0.488	2
UniProt:O43281-2 EFS			0.488	2
UniProt:Q8TF50 ZN526			0.488	2
UniProt:Q9NZQ3-3 NCKIPSD			0.488	2
UniProt:Q8N680 ZBTB2			0.488	2
UniProt:O75553-5 DAB1			0.488	2
UniProt:Q8NFH5 NUP35	1	NUP35 [nuclear envelope] (R-HSA-157748)	0.488	2
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.488	2
UniProt:A2BDD9 A2BDD9			0.488	2
UniProt:P60371 KRTAP10-6	1	KRTAP10-6 [cytosol] (R-HSA-6810247)	0.488	2
UniProt:P13349 MYF5	1	MYF5 [nucleoplasm] (R-HSA-445158)	0.488	2
UniProt:P15407 FOSL1			0.488	2
IntAct:EBI-11953908 CBFA2T3			0.488	2
UniProt:Q99081-3 TCF12			0.488	2
UniProt:Q9BVG8-5 KIFC3			0.488	2
UniProt:P50221 MEOX1			0.488	2
UniProt:Q9H7P9 PLEKHG2	1	PLEKHG2 [cytosol] (R-HSA-195043)	0.488	2
UniProt:P55198 AF17			0.488	2
UniProt:Q96IF1 AJUBA	3	p-S-AJUBA [cytosol] (R-HSA-2574841) AJUBA [nucleoplasm] (R-HSA-5687935) AJUBA [cytosol] (R-HSA-2564698)	0.488	2
UniProt:P26367 PAX6	1	PAX6 [nucleoplasm] (R-HSA-3009044)	0.488	2
UniProt:P40424 PBX1	1	PBX1 [nucleoplasm] (R-HSA-453045)	0.488	2
UniProt:P49639 HOXA1	1	HOXA1 [nucleoplasm] (R-HSA-5617464)	0.488	2
UniProt:P01100 FOS	2	p-T325,T331,S362,S374-FOS [nucleoplasm] (R-HSA-450283) FOS [nucleoplasm] (R-HSA-450216)	0.488	2