14-3-3 proteins bind AKT-phosphorylated FOXO4

Stable Identifier
R-HSA-9614564
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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Nuclear exclusion and cytoplasmic retention of AKT-phosphorylated FOXO4 is promoted by binding of FOXO4 to 14-3-3 zeta (YWHAZ) (Obsilova et al. 2005, Boura et al. 2007, Silhan et al. 2009).

Literature References
PubMed ID Title Journal Year
17244620 Both the N-terminal loop and wing W2 of the forkhead domain of transcription factor Foxo4 are important for DNA binding

Boura, E, Silhan, J, Herman, P, Vecer, J, Sulc, M, Teisinger, J, Obsilova, V, Obsil, T

J. Biol. Chem. 2007
19416966 14-3-3 protein masks the DNA binding interface of forkhead transcription factor FOXO4

Silhan, J, Vacha, P, Strnadova, P, Vecer, J, Herman, P, Sulc, M, Teisinger, J, Obsilova, V, Obsil, T

J. Biol. Chem. 2009
16114898 14-3-3 Protein interacts with nuclear localization sequence of forkhead transcription factor FoxO4

Obsilova, V, Vecer, J, Herman, P, Pabianova, A, Sulc, M, Teisinger, J, Boura, E, Obsil, T

Biochemistry 2005
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