14-3-3 proteins bind AKT-phosphorylated FOXO1

Stable Identifier
R-HSA-9614423
Type
Reaction [binding]
Species
Homo sapiens
Compartment
ReviewStatus
5/5
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Nuclear exclusion and cytoplasmic retention of AKT-phosphorylated FOXO1 is promoted by binding of FOXO1 to 14-3-3 proteins: YWHAZ (14-3-3 zeta), YWHAQ (14-3-3 theta), YWHAB (14-3-3 beta) and YWHAG (14-3-3 gamma) (Rena et al. 2001).
Literature References
PubMed ID Title Journal Year
11237865 Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting

Cohen, P, Guo, S, Prescott, AR, Rena, G, Unterman, TG

Biochem. J. 2001
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