Reactome | RGS6 [plasma membrane]

RGS6 [plasma membrane]

Stable Identifier

R-HSA-939789

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Regulator of G-protein signaling 6, RGS6_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P49758 RGS6

Gene Names

RGS6

Chain

chain:1-472

Reference Genes

BioGPS Gene:9628 RGS6

COSMIC (genes):RGS6 RGS6

CTD Gene:9628 RGS6

dbSNP Gene:9628 RGS6

ENSEMBL:ENSG00000182732 RGS6

ENSEMBL_homo_sapiens_GENE:ENSG00000182732.18 RGS6

HGNC:10002 RGS6

KEGG Gene (Homo sapiens):9628 RGS6

Monarch:9628 RGS6

NCBI Gene:9628 RGS6

OMIM:603894 RGS6

UCSC:P49758 RGS6

Reference Transcript

Other Identifiers

11729485_a_at

11729486_at

11729487_at

11750930_a_at

11750931_x_at

11752774_a_at

16786064

210270_PM_at

210270_at

211448_PM_s_at

211448_s_at

214538_PM_x_at

214538_x_at

236726_PM_at

236726_at

3543014

3543025

3543027

3543028

3543031

3543097

3543130

3543132

3543133

3543142

3543146

3543150

3543152

3543153

3543156

3543161

3543162

3543163

3543175

3543179

3543183

3543184

3543185

3543187

3543209

3543210

3543211

3543212

3543213

3543214

3543215

3543216

3543217

3543218

3543219

3543220

3543221

3543222

3543223

3543224

3543225

3543226

3543227

3543228

3543229

39656_at

52713_at

7975482

9628

A_14_P105388

A_14_P131676

A_23_P205666

A_32_P126557

A_33_P3212022

GE62684

GE81379

GE859457

GE88336

GO:0003824

GO:0003924

GO:0005096

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0005886

GO:0007186

GO:0008277

GO:0009968

GO:0016020

GO:0016787

GO:0023052

GO:0035556

GO:0043005

GO:0043226

GO:0043547

GO:0098772

HMNXSV003017002

HMNXSV003056445

Hs.31755.0.A1_3p_at

Hs.3221.2.S1_3p_a_at

Hs.3221.2.S1_3p_x_at

ILMN_1778267

L40394_at

PH_hs_0021751

PH_hs_0025427

PH_hs_0031728

TC14000435.hg

TC14001761.hg

g4972616_3p_a_at

g5107938_3p_at

Participates

as a candidate of

RGS7,RGS9,(RGS6,RGS11) [plasma membrane] (Homo sapiens)

as a member of

Inferred To

RSG7 [plasma membrane] (Drosophila melanogaster)

egl-10 [plasma membrane] (Caenorhabditis elegans)

RGS6 [plasma membrane] (Bos taurus)

RGS6 [plasma membrane] (Canis familiaris)

RGS6 [plasma membrane] (Gallus gallus)

RGS6 [plasma membrane] (Sus scrofa)

rgs6 [plasma membrane] (Xenopus tropicalis)

hm:zeh0300 [plasma membrane] (Danio rerio)

Rgs6 [plasma membrane] (Mus musculus)

Cross References

RefSeq

NP_001191346.1, XP_016877319.1, NP_004287.3, NP_001191348.1, NP_001191352.1, NP_001191347.1, XP_016877318.1, XP_016877321.1, NP_001191351.1, NP_001191350.1, NP_001191345.1, XP_016877323.1, XP_016877315.1, NP_001191353.1, NP_001191349.1

Guide to Pharmacology - Targets

2815

OpenTargets

ENSG00000182732

HPA

ENSG00000182732-RGS6

GeneCards

P49758

Ensembl

ENST00000407322, ENSG00000182732, ENSP00000450936, ENSP00000450858, ENST00000556437, ENST00000406236, ENST00000404301, ENSP00000451855, ENSP00000451030, ENST00000554474, ENSP00000384218, ENST00000553525, ENSP00000451912, ENSP00000347699, ENSP00000384612, ENSP00000452331, ENST00000555571, ENST00000554782, ENST00000553530, ENST00000355512, ENSP00000385243

PRO

P49758

Pharos - Targets

P49758

PDB

2ES0

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P08238 HSP90AB1	6	HSP90AB1 [secretory granule lumen] (R-HSA-6801477) HSP90AB1 [extracellular region] (R-HSA-6806463) HSP90AB1 [ficolin-1-rich granule lumen] (R-HSA-6801491) HSP90AB1 [cytosol] (R-HSA-419617) HSP90AB1 [nucleoplasm] (R-HSA-5082399) HSP90AB1 [lysosomal lumen] (R-HSA-9622846)	0.524	2