Reactome | RGS8 [plasma membrane]

RGS8 [plasma membrane]

Stable Identifier

R-HSA-939769

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Regulator of G-protein signaling 8, RGS8_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P57771 RGS8

Gene Names

RGS8

Chain

chain:1-180

Reference Genes

BioGPS Gene:85397 RGS8

COSMIC (genes):RGS8 RGS8

CTD Gene:85397 RGS8

dbSNP Gene:85397 RGS8

ENSEMBL:ENSG00000135824 RGS8

ENSEMBL_homo_sapiens_GENE:ENSG00000135824.13 RGS8

HGNC:16810 RGS8

KEGG Gene (Homo sapiens):85397 RGS8

Monarch:85397 RGS8

NCBI Gene:85397 RGS8

OMIM:607189 RGS8

UCSC:P57771 RGS8

Reference Transcript

Other Identifiers

11746590_a_at

16697025

224390_PM_s_at

224390_s_at

244675_PM_at

244675_at

2447183

2447184

2447186

2447187

2447188

2447189

2447190

2447191

2447193

2447194

2447195

2447196

2447197

2447198

2447199

2447200

2447205

2447206

2447208

2447209

2447211

2447212

2447213

2447214

2447215

48453_at

7922727

85397

A_23_P103424

GE519916

GO:0003824

GO:0003924

GO:0005096

GO:0005515

GO:0005634

GO:0005886

GO:0007186

GO:0007213

GO:0009898

GO:0009968

GO:0016020

GO:0016787

GO:0023052

GO:0030425

GO:0032809

GO:0042995

GO:0043204

GO:0043226

GO:0043547

GO:0045202

GO:0060159

GO:0098772

HMNXSV003003814

HMNXSV003010143

HMNXSV003037479

Hs.20982.0.A1_3p_at

ILMN_1808215

PH_hs_0001807

PH_hs_0026377

TC01003609.hg

TC01005983.hg

g12017954_3p_s_at

p575

Participates

as a candidate of

RGS proteins active for G alpha (i) [plasma membrane] (Homo sapiens)

as a member of

RGS1,3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21 [plasma membrane] (Homo sapiens)

Inferred To

rgs-10 [plasma membrane] (Caenorhabditis elegans)

rgs-6 [plasma membrane] (Caenorhabditis elegans)

SST2 [plasma membrane] (Saccharomyces cerevisiae)

rgs-3 [plasma membrane] (Caenorhabditis elegans)

Rgs8 [plasma membrane] (Mus musculus)

Rgs8 [plasma membrane] (Rattus norvegicus)

Homologues of RGS8 [plasma membrane] (Caenorhabditis elegans)

Homologues of RGS8 [plasma membrane] (Dictyostelium discoideum)

Homologues of RGS8 [plasma membrane] (Saccharomyces cerevisiae)

RGS2 [plasma membrane] (Saccharomyces cerevisiae)

rgs1 [plasma membrane] (Schizosaccharomyces pombe)

RGS8 [plasma membrane] (Bos taurus)

RGS8 [plasma membrane] (Canis familiaris)

RGS8 [plasma membrane] (Dictyostelium discoideum)

RGS8 [plasma membrane] (Gallus gallus)

RGS8 [plasma membrane] (Sus scrofa)

rgs-8.1 [plasma membrane] (Caenorhabditis elegans)

rgs-11 [plasma membrane] (Caenorhabditis elegans)

rgs-4 [plasma membrane] (Caenorhabditis elegans)

rgs-7 [plasma membrane] (Caenorhabditis elegans)

rgs-9 [plasma membrane] (Caenorhabditis elegans)

rgs8 [plasma membrane] (Danio rerio)

rgs8 [plasma membrane] (Xenopus tropicalis)

Cross References

RefSeq

XP_016858126.1, XP_011508392.1, XP_005245612.1, XP_016858124.1, NP_001095920.1, XP_016858122.1, XP_016858120.1, NP_203131.1, XP_016858123.1, XP_016858121.1, XP_016858125.1, XP_011508391.1

Guide to Pharmacology - Targets

2813

OpenTargets

ENSG00000135824

HPA

ENSG00000135824-RGS8

ZINC - Substances

RGS8_HUMAN

GeneCards

P57771

Ensembl

ENSP00000258302, ENSP00000356528, ENST00000483095, ENSG00000135824, ENST00000258302, ENSP00000426289, ENST00000367556, ENST00000367557, ENSP00000511884, ENST00000515211, ENSP00000356527

ZINC target

P57771

PRO

P57771

Pharos - Targets

P57771

ZINC - Predictions - Purchasable

RGS8_HUMAN

PDB

5DO9, 2IHD, 2ODE

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3

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