K48polyUb-TRAF3 [cytosol]

Stable Identifier
R-HSA-936556
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
Synonyms
K48-polyubiquitin TRAF3
K48polyUb-TRAF3 [cytosol] icon
Locations in the PathwayBrowser for interactor UniProt:Q0D2K3 RIPP1
Literature References
PubMed ID Title Journal Year
19893624 The E3 ubiquitin ligase Triad3A negatively regulates the RIG-I/MAVS signaling pathway by targeting TRAF3 for degradation

Nakhaei, P, Mesplede, T, Solis, M, Sun, Q, Zhao, T, Yang, L, Chuang, TH, Ware, CF, Lin, R, Hiscott, J

PLoS Pathog 2009
External Reference Information
External Reference
Gene Names
TRAF3, CAP1, CRAF1
Chain
chain:1-568
Other Identifiers
0000940739
11742091_a_at
11743501_a_at
11759502_at
16789080
1FLK
1FLL
1KZZ
1L0A
1RF3
1ZMS
208315_3p_x_at
208315_x_at
221571_at
2933
2ECY
2GKW
3553338
3553346
3553358
3553359
3553363
3553364
3553367
3553368
3553370
3553374
3553382
3553383
3553384
3553386
3553388
37057_s_at
43952_at
7187
7977018
A6NHG8
A_23_P37068
A_32_P89837
AAA56753
AAA65732
AAA68195
AAC50112
AAD29276
AAH75086
AAH75087
AF110908
AK303172
AL117209
BAH13910
BC075086
BC075087
BX247977
CAD62311
CCDS55946
CCDS9975
ENSG00000131323
ENSP00000328003
ENSP00000376500
ENSP00000445998
ENSP00000454207
ENST00000347662
ENST00000392745
ENST00000392745.6
ENST00000539721
ENST00000539721.5
ENST00000560371
ENST00000560371.5
EntrezGene:7187
EntrezGene:TRAF3
g4507678_3p_a_at
g4507678_3p_at
g4507678_3p_x_at
GE59008
GO:0001817
GO:0002224
GO:0002376
GO:0003674
GO:0004842
GO:0005164
GO:0005515
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005739
GO:0005768
GO:0005829
GO:0005886
GO:0006464
GO:0006915
GO:0006950
GO:0007165
GO:0008063
GO:0008150
GO:0008219
GO:0008270
GO:0009058
GO:0009898
GO:0016567
GO:0016579
GO:0016740
GO:0019899
GO:0019901
GO:0019903
GO:0030162
GO:0031410
GO:0031625
GO:0031996
GO:0032088
GO:0032648
GO:0032991
GO:0033209
GO:0034641
GO:0035631
GO:0035666
GO:0042981
GO:0043167
GO:0043226
GO:0045087
GO:0046872
GO:0050688
H0YL25
H0YL26
H0YMI8
HGNC:12033
HPA002933
Hs.297660.1.S2_3p_at
ILMN_1793154
ILMN_2383774
IPR001293
IPR001841
IPR002083
IPR008974
IPR012227
IPR013083
IPR017907
IPR027128
IPR037304
L38509
LRG_229
LRG_229t1
MIM:601896
MIM:614849
NM_001199427
NM_003300
NM_145725
NP_001186356
NP_003291
NP_663777
PF02176
PH_hs_0015383
PH_hs_0038599
SM00061
TC14000786.hg
TRAF3
TRAF3-203
TRAF3-204
TRAF3-208
U15637
U15637_s_at
U19260
U21092
UPI000000CBF9
UPI0001E88EE1
XM_011537118
XM_017021617
XM_017021618
XP_011535420
XP_016877106
XP_016877107
Participant Of
Other forms of this molecule
Modified Residues
Name
ubiquitinylated lysine (K48polyUb [cytosol]) at unknown position
Modification
K48polyUb [cytosol]
PsiMod Name
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Interactors (40)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:Q99558 MAP3K14  5 0.783 5
 UniProt:Q92844 TANK  2 0.77 6
 UniProt:Q13546 RIPK1  9 0.675 4
 UniProt:Q8TDR0 TRAF3IP1  2 0.639 8
 UniProt:O00463 TRAF5      0.635 3
 UniProt:O43353 RIPK2  2 0.633 5
 UniProt:O95721 SNAP29  3 0.621 3
 UniProt:P36941 LTBR  1 0.564 2
 UniProt:Q9HAV5 EDA2R  1 0.564 2
 UniProt:Q15628 TRADD  1 0.547 2
 UniProt:Q13490 BIRC2  5 0.527 3
 UniProt:P61964 WDR5  1 0.524 2
 UniProt:P25942 CD40      0.508 3
 UniProt:Q9QYP6 AZI2      0.499 2
 UniProt:P15314  1 0.499 2
 UniProt:A2APF7 A2APF7      0.499 2
 UniProt:Q52MB2 CC184      0.488 2
 UniProt:Q5T681 CJ062      0.488 2
 UniProt:Q8IYE1 CCD13      0.488 2
 UniProt:Q6ZSB9 ZBT49      0.488 2
 UniProt:Q7KZS0 Q7KZS0      0.488 2
 UniProt:Q8NAM6 ZSCA4      0.488 2
 UniProt:Q96D03 DDT4L      0.488 2
 UniProt:Q8N9N2-2 ASCC1      0.488 2
 UniProt:Q9UKD1 GMEB2      0.488 2
 UniProt:O75928-2 PIAS2  1 0.488 2
 UniProt:Q9Y547 HSPB11  2 0.488 2
 UniProt:Q16543 CDC37  1 0.488 2
 UniProt:Q13114 TRAF3  5 0.488 2
 UniProt:Q86UB2 BIVM      0.488 2
 UniProt:Q8TBB1 LNX1  1 0.488 2
 UniProt:Q0D2K3 RIPP1      0.488 2
 UniProt:P28062-2 PSMB8      0.488 2
 IntAct:EBI-12191689 HEMGN      0.488 2
 UniProt:P54725 RAD23A  1 0.488 2
 UniProt:Q17RL8 Q17RL8      0.488 2
 UniProt:P78317 RNF4  2 0.488 2
 UniProt:Q96HA1-2 POM121      0.488 2
 UniProt:Q96PC2 IP6K3  1 0.488 4
 UniProt:Q96HA8 NTAQ1      0.488 2