apoTF binds 2Fe3+ to form holoTF

Stable Identifier
R-HSA-917888
Type
Reaction
Species
Homo sapiens
Compartment
Synonyms
apo-Transferrin is loaded with two iron ions
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Transferrin (TF) is the main transporter of iron in the blood. The apo-form of TF can take up two ferric iron ions (Fe3+) to form holoTF (Wally et al. 2006).

Literature References
PubMed ID Title Journal Year
16793765 The crystal structure of iron-free human serum transferrin provides insight into inter-lobe communication and receptor binding

Wally, J, Halbrooks, PJ, Vonrhein, C, Rould, MA, Everse, SJ, Mason, AB, Buchanan, SK

J Biol Chem 2006
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