Reactome | VPS4A [cytosol]

VPS4A [cytosol]

Stable Identifier

R-HSA-917732

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Vacuolar protein sorting-associated protein 4A, VPS4A_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UN37 VPS4A

Gene Names

VPS4A, VPS4

Chain

chain:1-437

Reference Genes

BioGPS Gene:27183 VPS4A

COSMIC (genes):VPS4A VPS4A

CTD Gene:27183 VPS4A

dbSNP Gene:27183 VPS4A

ENSEMBL:ENSG00000132612 VPS4A

ENSEMBL_homo_sapiens_GENE:ENSG00000132612.16 VPS4A

HGNC:13488 VPS4A

KEGG Gene (Homo sapiens):27183 VPS4A

Monarch:27183 VPS4A

NCBI Gene:27183 VPS4A

OMIM:609982 VPS4A

UCSC:Q9UN37 VPS4A

Reference Transcript

RefSeq:NM_013245.2 VPS4A

Other Identifiers

11745333_a_at

16820572

217913_PM_at

217913_at

27183

3666650

3666651

3666652

3666657

3666659

3666660

3666661

3666662

3666663

3666664

3666665

3666667

3666669

3666673

3666674

3666675

3666676

3666677

3666678

3666679

3666682

3666683

44787_s_at

45802_at

57935_at

70639_at

7996919

A_14_P114896

A_14_P114928

A_23_P329772

GE62753

GO:0000166

GO:0000278

GO:0000910

GO:0000916

GO:0000922

GO:0001778

GO:0003824

GO:0005515

GO:0005524

GO:0005576

GO:0005615

GO:0005634

GO:0005635

GO:0005643

GO:0005737

GO:0005764

GO:0005768

GO:0005769

GO:0005770

GO:0005773

GO:0005774

GO:0005813

GO:0005815

GO:0005819

GO:0005829

GO:0005856

GO:0005886

GO:0006622

GO:0006886

GO:0006900

GO:0006914

GO:0006996

GO:0006997

GO:0006998

GO:0007010

GO:0007033

GO:0007049

GO:0007059

GO:0007080

GO:0007084

GO:0009838

GO:0010008

GO:0015031

GO:0016020

GO:0016192

GO:0016197

GO:0016236

GO:0016787

GO:0016887

GO:0019076

GO:0023052

GO:0030163

GO:0030496

GO:0031410

GO:0031468

GO:0031902

GO:0032367

GO:0032466

GO:0032880

GO:0034058

GO:0036258

GO:0039702

GO:0042060

GO:0043162

GO:0043226

GO:0044877

GO:0044878

GO:0046761

GO:0048471

GO:0048856

GO:0051301

GO:0061024

GO:0061640

GO:0061738

GO:0061764

GO:0061952

GO:0070062

GO:0071985

GO:0072319

GO:0072659

GO:0090148

GO:0090543

GO:0090611

GO:0097352

GO:0140014

GO:0140545

GO:0140657

GO:1903076

GO:1903543

GO:1903774

GO:1904896

GO:1904903

GO:1904949

HMNXSV003051082

ILMN_1708946

PH_hs_0026702

TC16000567.hg

g7019568_3p_at

Participates

as a component of

as an input of

as an output of

Inferred To

Vps4 [cytosol] (Drosophila melanogaster)

vps-4 [cytosol] (Caenorhabditis elegans)

zgc:153907 [cytosol] (Danio rerio)

VPS4A [cytosol] (Bos taurus)

VPS4A [cytosol] (Canis familiaris)

VPS4A [cytosol] (Dictyostelium discoideum)

VPS4A [cytosol] (Gallus gallus)

VPS4A [cytosol] (Mus musculus)

VPS4A [cytosol] (Rattus norvegicus)

VPS4A [cytosol] (Saccharomyces cerevisiae)

VPS4A [cytosol] (Schizosaccharomyces pombe)

VPS4A [cytosol] (Sus scrofa)

vps4a [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_037377.1

OpenTargets

ENSG00000132612

IntEnz

3.6.4.6

GeneCards

Q9UN37

HPA

ENSG00000132612-VPS4A

Ensembl

ENSP00000254950, ENSG00000132612, ENST00000254950

PRO

Q9UN37

Pharos - Targets

Q9UN37

HMDB Protein

HMDBP12005

PDB

1YXR, 2JQ9, 2K3W

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.788	9
UniProt:Q7LBR1 CHM1B			0.592	4
UniProt:Q9HD42-1 CHMP1A			0.558	2
UniProt:O95833 CLIC3			0.556	3
UniProt:Q5S007 LRRK2	1	LRRK2 [cytosol] (R-HSA-5661173)	0.527	3